Evidence map›Paper›PMID 36246263›Full record

ArticleFrontiers in microbiology2022

Integrative analysis of the mouse fecal microbiome and metabolome reveal dynamic phenotypes in the development of colorectal cancer.

Jingjing Liu, Mingyang Qi, Chengchao Qiu, Feng Wang, Shaofei Xie, Jian Zhao, Jing Wu, Xiaofeng Song

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Nutrients · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jingjing LiuDepartment of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China.
Mingyang QiDepartment of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China.
Chengchao QiuDepartment of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China.
Feng WangState Key Laboratory of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Pharmaceutical Co., Ltd., Nanjing, China.
Shaofei XieState Key Laboratory of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Pharmaceutical Co., Ltd., Nanjing, China.
Jian ZhaoDepartment of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China.
Jing WuSchool of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China.
Xiaofeng SongDepartment of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China.
Nanjing University of Aeronautics and Astronautics · CNSimcere Pharmaceutical (China) · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiome and its interaction with host have been implicated as the causes and regulators of colorectal cancer (CRC) pathogenesis. However, few studies comprehensively investigate the compositions of gut bacteria and their interactions with host at the early inflammatory and cancerous stages of CRC. In this study, mouse fecal samples collected at inflammation and CRC were subjected to microbiome and metabolome analyses. The datasets were analyzed individually and integratedly using various bioinformatics approaches. Great variations in gut microbiota abundance and composition were observed in inflammation and CRC. The abundances of

Indexed as

colorectal cancergut microbiotainflammationmetabolomemicrobiome

Identifiers

PMID36246263
PMCPMC9554438
OpenAlexW4297543263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.