Evidence map›Paper›PMID 36246244›Full record

ReviewFrontiers in microbiology2022

Dissemination and prevalence of plasmid-mediated high-level tigecycline resistance gene

Shaqiu Zhang, Jinfeng Wen, Yuwei Wang, Mingshu Wang, Renyong Jia, Shun Chen, Mafeng Liu, Dekang Zhu, Xinxin Zhao, Ying Wu and 8 more

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Evolution, Mechanisms, and Therapeutic Implications of Mobile Tetracycline Destructases.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  5. Article
  6. Article
  7. Phenotypic and genome-based characterization ofFrontiers in microbiology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Emergence ofCurrent research in microbial sciences · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Emergence of plasmid-borneMicrobiology spectrum · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Shaqiu ZhangAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Jinfeng WenAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yuwei WangMianyang Academy of Agricultural Sciences, Mianyang, China.
Mingshu WangAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Renyong JiaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Shun ChenAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Mafeng LiuAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Dekang ZhuAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Xinxin ZhaoAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ying WuAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Qiao YangAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Juan HuangAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Xumin OuAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Sai MaoAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Qun GaoAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Di SunAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Bin TianAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Anchun ChengAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the large-scale use of antibiotics, antibiotic resistant bacteria (ARB) continue to rise, and antibiotic resistance genes (ARGs) are regarded as emerging environmental pollutants. The new tetracycline-class antibiotic, tigecycline is the last resort for treating multidrug-resistant (MDR) bacteria. Plasmid-mediated horizontal transfer enables the sharing of genetic information among different bacteria. The tigecycline resistance gene

Indexed as

antibiotic resistant bacteriaone healthplasmid-mediatedtet(X4)tigecycline resistance genetransmission

Identifiers

PMID36246244
PMCPMC9557194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.