Evidence map›Paper›PMID 36246229›Full record

ArticleFrontiers in microbiology2022

Michael P Jeffrey, Chad W MacPherson, Thomas A Tompkins, Julia M Green-Johnson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michael P JeffreyApplied Bioscience Graduate Program and the Faculty of Science, Ontario Tech University, Oshawa, ON, Canada.
Chad W MacPhersonNutraPharma Consulting Services, Inc., Montreal, QC, Canada.
Thomas A TompkinsLallemand Bio-Ingredients, Inc., Montreal, QC, Canada.
Julia M Green-JohnsonApplied Bioscience Graduate Program and the Faculty of Science, Ontario Tech University, Oshawa, ON, Canada.
University of Ontario Institute of Technology · CALallemand (Canada) · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Certain lactic acid bacteria (LAB) are associated with immune modulatory activities including down-regulation of pro-inflammatory gene transcription and expression. While host antigen-presenting cells (APCs) and intestinal epithelial cells (IEC) can interact directly with both pathogenic and commensal bacteria through innate immune pattern recognition receptors, recent evidence indicates indirect communication through secreted molecules is an important inter-domain communication mechanism. This communication route may be especially important in the context of IEC and APC interactions which shape host immune responses within the gut environment. We have previously shown that the

Indexed as

antigen-presenting cell (APC)cytokinesintestinal epithelial cellLacticaseibacillus rhamnosus R0011 secretomemacrophage inhibitory factor (MIF)monocyteSalmonella enterica serovar Typhimurium secretomeTranswell

Identifiers

PMID36246229
PMCPMC9554441
OpenAlexW4297541830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.