ArticleFrontiers in physiology2022
A targeted metabolic analysis of football players and its association to player load: Comparison between women and men profiles.
Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Socceromics: A Systematic Review of Omics Technologies to Optimize Performance and Health in Soccer.International journal of molecular sciences · 2026Pooled it
- Metabolomics analyses and physical interventions in soccer: a systematic review.Metabolomics : Official journal of the Metabolomic Society · 2024Pooled it
- Urinary metabolomic signatures of muscle injury and recovery in elite football players.Metabolomics : Official journal of the Metabolomic Society · 2026Observational
- The effects of French contrast method on explosive power and speed-related skills in female soccer players: a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2026Article
- Association Between Habitual Food Intake and Energy Metabolism-Related Urine Metabolites in Female Soccer Players.Molecular nutrition & food research · 2026Article
- Energy production pathways of female soccer players during championships: a metabolomics approach.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026Article
- Epigenetic signatures, age acceleration, and injury risk in elite female and male soccer players.Scientific reports · 2025Article
- Non-contact injury incidence in professional women's football depends on the starting status of the player.Biology of sport · 2025Article
- Article
- Metabolomic profiling of elite female soccer players: urinary biomarkers over a championship season.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Mass Sportrometry: An annual look back at applications of mass spectrometry in sport and exercise science.Analytical science advances · 2023Review
- Editorial: New technologies and statistical models applied to sports and exercise science research: methodological, technical and practical considerations.Frontiers in sports and active living · 2023Article
- Comparison of the effects of pea protein and whey protein on the metabolic profile of soccer athletes: a randomized, double-blind, crossover trial.Frontiers in nutrition · 2023Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Professional athletes undertake a variety of training programs to enhance their physical performance, technical-tactical skills, while protecting their health and well-being. Regular exercise induces widespread changes in the whole body in an extremely complex network of signaling, and evidence indicates that phenotypical sex differences influence the physiological adaptations to player load of professional athletes. Despite that there remains an underrepresentation of women in clinical studies in sports, including football. The objectives of this study were twofold: to study the association between the external load (EPTS) and urinary metabolites as a surrogate of the adaptation to training, and to assess the effect of sex on the physiological adaptations to player load in professional football players. Targeted metabolic analysis of aminoacids, and tryptophan and phenylalanine metabolites detected progressive changes in the urinary metabolome associated with the external training load in men and women's football teams. Overrepresentation analysis and multivariate analysis of metabolic data showed significant differences of the effect of training on the metabolic profiles in the men and women teams analyzed. Collectively, our results demonstrate that the development of metabolic models of adaptation in professional football players can benefit from the separate analysis of women and men teams, providing more accurate insights into how adaptation to the external load is related to changes in the metabolic phenotypes. Furthermore, results support the use of metabolomics to understand changes in specific metabolic pathways provoked by the training process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.