Evidence map›Paper›PMID 36246043›Full record

ArticleChemCatChem2022

Cascade Catalysis Through Bifunctional Lipase Metal Biohybrids for the Synthesis of Enantioenriched O-Heterocycles from Allenes.

Janne M Naapuri, Noelia Losada-Garcia, Robin Alexander Rothemann, Manuel Carmona Pichardo, Martin H G Prechtl, Jose M Palomo, Jan Deska

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemCatChem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Janne M NaapuriDepartment of Chemistry University of Helsinki A. I. Virtasen aukio 1 00560 Helsinki Finland.
Noelia Losada-GarciaInstituto de Catalisis y Petroleoquimica (ICP) CSIC C/ Marie Curie 2 28049 Madrid Spain.
Robin Alexander RothemannDepartment of Chemistry Aalto University Kemistintie 1 02150 Espoo Finland.ORCID 0000-0002-9502-5360
Manuel Carmona PichardoDepartment of Chemistry Aalto University Kemistintie 1 02150 Espoo Finland.
Martin H G PrechtlInstituto Superior Técnico Universidade de Lisboa Av. Rovisco Pais 1 1049-001 Lisboa Portugal.ORCID 0000-0003-2155-8006
Jose M PalomoInstituto de Catalisis y Petroleoquimica (ICP) CSIC C/ Marie Curie 2 28049 Madrid Spain.ORCID 0000-0002-6464-1216
Jan DeskaDepartment of Chemistry University of Helsinki A. I. Virtasen aukio 1 00560 Helsinki Finland.ORCID 0000-0003-4622-2365
Aalto University · FIConsejo Superior de Investigaciones Científicas · ESUniversity of Helsinki · FIUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipase/metal nanobiohybrids, generated by growth of silver or gold nanoparticles on protein matrixes are used as highly effective dual-activity heterogeneous catalysts for the production of enantiomerically enriched 2,5-dihydrofurans from allenic acetates in a one-pot cascade process combining a lipase-mediated hydrolytic kinetic resolution with a metal-catalyzed allene cycloisomerization. Incorporating a novel strategy based on enzyme-polymer bioconjugates in the nanobiohybrid preparation enables excellent conversions in the process.

Indexed as

cascadesdual catalysisheterocycleslipasesnanoparticles

Identifiers

PMID36246043
PMCPMC9544965
OpenAlexW4280626368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.