ArticleJournal of dental anesthesia and pain medicine2022
Buffered articaine infiltration for primary maxillary molar extractions: a randomized controlled study.
Article in Journal of dental anesthesia and pain medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Effectiveness of Low-level Laser Therapy on Reversing Soft-tissue Local Anesthesia among 5- to 8-year-old Children: A Randomized Split-mouth Clinical Trial.International journal of clinical pediatric dentistry · 2026Article
- Effectiveness of buffered local anesthetic solutions in pediatric nerve blocks and infiltration anesthesia: a systematic review and meta-analysis.Journal of dental anesthesia and pain medicine · 2026Review
- Buffered 4% Articaine Reduces Pain and Enhances Anesthesia in Maxillary Third Molar Extractions: A Randomized, Double-Blind Split-Mouth Study.Biomedicines · 2024Article
- Anesthetic efficacy of buffered 4% articaine for mandibular first molar infiltration: a crossover clinical trial.Journal of dental anesthesia and pain medicine · 2023Article
- Buffered versus Non-buffered Local Anaesthesia in Minor Oral Surgery - A Comparative Study.Annals of maxillofacial surgeryArticle
- Effectiveness of buffered and non-buffered lignocaine and articaine in children aged 6-12 years undergoing invasive dental procedures: A randomized clinical trial.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dental pain management is an important aspect of patient management in pediatric dentistry. Articaine is considered the most successful anesthetic agent for infiltration anesthesia. Buffered articaine has been observed to have faster onset and longer duration of action with less pain on injection. The aim of this study was to evaluate and compare pain on injection, onset of action, and pain during extraction using buffered (using Sodium bicarbonate (NaHCO Methods: Seventy children who required extraction of maxillary primary molars were enrolled in this triple-blind randomized study. Children undergoing extraction were randomly divided into two groups, with 35 in each group. The study group was the buffered articaine group; the control group was the non-buffered articaine group. Buccal and palatal infiltrations were administered with either buffered or non-buffered articaine. Subjective evaluation was done for pain on injection, pain during extraction using Wong-Baker Faces Pain Rating Scale (WBFPR) and onset of anesthesia in seconds. Pain on injection, pain during extraction were objectively evaluated using Sound Eye Motor (SEM) scale and onset of anesthesia was also evaluated objectively by pricking with sharp dental probe. Results: The outcome was, significantly less pain on injection and significantly faster onset of anesthesia with significantly less pain during extraction for both subjective and objective evaluations in the buffered articaine group. Subgroup analysis was also performed and it showed variable results, with only significant difference for WBFPR scores in age subgroup 4-7 years for palatal infiltration. Conclusion: Less pain on injection, faster onset of anesthesia, and less pain during extraction were observed when buffered articaine was used for maxillary primary molar extraction.
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