Evidence map›Paper›PMID 36245887›Full record

ArticleFrontiers in psychiatry2022

The neuropeptide Y single-nucleotide polymorphism

Xiaojie Wei, Fangfang Cai, Siyao Zhou, Jinjing Zhang, Kewei Xu, Guanghui Shen, Huankun Sun, Fan Yang, Liuzhi Hong, Yang Zou and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Xiaojie WeiAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo, China.
Fangfang CaiSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Siyao ZhouSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Jinjing ZhangAffiliated Cixi Hospital, Wenzhou Medical University, Ningbo, China.
Kewei XuSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Guanghui ShenSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Huankun SunSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Fan YangSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Liuzhi HongSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Yang ZouSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Yu-Hsin ChenDepartment of Psychology, College of Liberal Arts, Wenzhou-Kean University, Wenzhou, China.
Yanlong LiuSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Li ChenSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Fan WangBeijing Hui-Long-Guan Hospital, Peking University, Beijing, China.
Wei WangSchool of Mental Health, Wenzhou Medical University, Wenzhou, China.
Wenzhou Medical University · CNJinzhou Kangning Hospital · CNPeking University · CNWenzhou-Kean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies suggest that alcohol dependence is associated with depression, however, the effect of alcohol dependence varies from individual to individual, which may be due to different genetic backgrounds. The interactions between alcohol dependence and different gene polymorphisms may finally shape the onset of depression. Neuropeptide Y (NPY), which can maintain homeostasis from high-stress stimulation, may protect individuals from the onset of depression. Here, we explored whether the NPY Methods: A total of 455 males with alcohol dependence were recruited. The scale of Michigan Alcoholism Screening Test (MAST) and Self-Depression Scale (SDS) were respectively used to analyze the condition of alcohol dependence and depression. Genomic DNA was extracted from each blood sample and NPY polymorphisms were genotyped. The interaction between NPY Results: Alcohol dependence was positively correlated with depression. CC homozygotes of NPY Conclusion: NPY

Indexed as

alcohol use disorderdepressive disorderinteractionNPY rs16147:T>CSNP

Identifiers

PMID36245887
PMCPMC9558829
OpenAlexW4298000176

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.