Evidence map›Paper›PMID 36245599›Full record

ArticleJournal of thoracic disease2022

Skeletal muscle and related protein expression as prognostic factors in thymic squamous cell carcinoma.

Keita Nakanishi, Naoki Ozeki, Hisashi Tateyama, Yuka Kadomatsu, Harushi Ueno, Masaki Goto, Shota Nakamura, Koichi Fukumoto, Toyofumi Fengshi Chen-Yoshikawa

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Keita NakanishiDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Naoki OzekiDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hisashi TateyamaDepartment of Pathology, Clinical Laboratory, Kasugai Municipal Hospital, Kasugai, Japan.
Yuka KadomatsuDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Harushi UenoDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Masaki GotoDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shota NakamuraDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Koichi FukumotoDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Toyofumi Fengshi Chen-YoshikawaDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nagoya University · JPKasugai Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sarcopenia and its marker, the psoas muscle index (PMI), have attracted attention as prognostic factors for various types of cancers. The fragile X-related 1 ( Methods: We retrospectively investigated the prognostic significance of PMI in 34 patients who underwent TSQCC resection, considering the status of FXR1 and tumor programmed death-ligand 1 (PD-L1). PMI was calculated from the bilateral psoas muscle using preoperative computed tomography (CT). Patients were divided into two groups: low PMI (<58.2%, n=17) and normal PMI (≥58.2%, n=17). Immunohistochemical analysis was performed to determine the FXR1 and PD-L1 expression levels. Results: Low PMI was significantly associated with worse overall survival (OS) (5-year survival rate; 86% Conclusions: Our findings suggest that PMI might be considered as a potential prognostic factor in TSQCC and that FXR1 is widely expressed regardless of the PMI status. Skeletal muscle mass may play a role in the prognosis of TSQCC.

Indexed as

fragile X-related 1 (FXR1) geneprogrammed death-ligand 1 (PD-L1)psoas muscle index (PMI)surgeryThymic squamous cell carcinoma (TSQCC)

Identifiers

PMID36245599
PMCPMC9562531
OpenAlexW4288468212

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.