Evidence map›Paper›PMID 36245555›Full record

ArticleGenetics research2022

Effects of Genetic Variants in the Nicotine Metabolism Pathway on Smoking Cessation.

Huijie Li, Qiang Wang, Suyun Li, Chongqi Jia

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Huijie LiShandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.ORCID 0000-0003-0063-3513
Qiang WangDepartment of Epidemiology, Weifang Medical University, Weifang, China.ORCID 0000-0003-3692-3870
Suyun LiDepartment of Epidemiology and Health Statistics, Qingdao University, Qingdao, China.
Chongqi JiaDepartment of Epidemiology, Shandong University, Jinan, China.ORCID 0000-0001-9099-638X
Shandong University · CNQingdao University · CNWeifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We aimed to investigate the associations of various genetic variants in the nicotine metabolism pathway with smoking cessation (SC) in the Chinese Han population. Method: A case-control study was conducted where 363 successful smoking quitters were referred to as cases, and 345 failed smoking quitters were referred to as controls. A total of 42 genetic variants in 10 genes were selectedand genotyped. The weighted gene score was applied to analyze the whole gene effect. Logistic regression was used to explore associations of each genetic variant and gene score with smoking cessation. Results: Our study found that the variants Conclusion: This study revealed that genetic variants in the nicotine metabolic pathway were associated with smoking cessation in the Chinese Han population.

Indexed as

Smoking CessationCase-Control StudiesCytochrome P-450 CYP2B6Cytochrome P-450 CYP2D6GlucuronosyltransferaseHumansNicotineCytochrome P-450 CYP2B6Cytochrome P-450 CYP2D6GlucuronosyltransferaseNicotineUGT2B10 protein, human

Identifiers

PMID36245555
PMCPMC9534651
OpenAlexW4297496423

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.