ArticleFrontiers in nutrition2022
A negative association between total cholesterol and bone mineral density in US adult women.
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Association between the nutritional risk index and postmenopausal osteoporosis in patients with type 2 diabetes mellitus.Frontiers in nutrition · 2026Article
- Observational
- Dietary phosphorus intake modifies the association between total cholesterol and lumbar spine bone mineral density: results from NHANES 2011-2016.Frontiers in nutrition · 2025Article
- Non-linear association of the platelet/high-density lipoprotein cholesterol ratio with bone mineral density a cross-sectional study.Lipids in health and disease · 2024Article
- Remnant cholesterol is associated with hip BMD and low bone mass in young and middle-aged men: a cross-sectional study.Journal of endocrinological investigation · 2024Article
- Application of machine learning algorithms to identify people with low bone density.Frontiers in public health · 2024Article
- TC and LDL-C are negatively correlated with bone mineral density in patients with osteoporosis.American journal of translational research · 2024Article
- Association between total cholesterol and lumbar bone density in Chinese: a study of physical examination data from 2018 to 2023.Lipids in health and disease · 2023Article
- The Effects of Claw Health and Bone Mineral Density on Lameness in Duroc Boars.Animals : an open access journal from MDPI · 2023Article
- The association of lipid metabolism with bone metabolism and the role of human traits: a Mendelian randomization study.Frontiers in endocrinology · 2023Article
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Authors and funding
6 authors.
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Abstract
Background: The association between serum total cholesterol (TC) and bone mineral density (BMD) is still controversial. We aimed to evaluate the association of serum TC with BMD in general US adult women. Methods: A cross-sectional study consisting of 7,092 (age range 20-85) participants from the National Health and Nutrition Examination Survey (NHANES) database was conducted. Weighted multivariate linear regression analyses were performed to evaluate association between serum TC and lumbar spine BMD. In addition, subgroup and interaction analysis were used in this study. Results: The serum TC was negatively correlated with lumbar spine BMD after adjusting for confounders. Subgroup analysis found that the strongest negative association mainly exists in women aged over 45 years with body mass index (BMI) < 24.9 kg/m Conclusions: This study found that serum TC exhibit an inverse association with lumbar spine BMD in Us women aged over 45 years. The measurement of serum TC may provide information for predicting poor bone health outcomes in these women.
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