Evidence map›Paper›PMID 36245484›Full record

ArticleFrontiers in nutrition2022

Functional role of cyanidin-3-O-glucoside in osteogenesis: A pilot study based on RNA-seq analysis.

Lin Chen, Bosen Hu, Xiaohong Wang, Yong Chen, Bo Zhou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lin ChenSchool of Public Health, Shenyang Medical College, Shenyang, China.
Bosen HuSchool of Public Health, Shenyang Medical College, Shenyang, China.
Xiaohong WangSchool of Public Health, Shenyang Medical College, Shenyang, China.
Yong ChenCentral Hospital Affiliated to Shenyang Medical College, Shenyang, China.
Bo ZhouSchool of Public Health, Shenyang Medical College, Shenyang, China.
Shenyang Medical College · CNCentral Hospital Affiliated to Shenyang Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyanidin-3-O-glucoside (C3G) is the most widely distributed anthocyanin and it can reportedly reduce the risk of osteoporosis, but the molecular mechanism by which C3G promotes bone formation is poorly understood. In the current study, RNA sequencing (RNA-seq) was used to investigate the mechanism of action of C3G in osteogenesis. MC3T3-E1 mouse osteoblasts were divided into a C3G (100 μmol/L)-treated group and a vehicle-treated control group, and differentially expressed genes (DEGs) in groups were evaluated

Indexed as

Atp6v0cCx3cl1cyanidin-3-O-glucosideLy6aMC3T3-E1 cellsosteogenesisRNA-sequencing

Identifiers

PMID36245484
PMCPMC9562617
OpenAlexW4298141314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.