ArticleJournal of the National Cancer Institute2022
Use of Straighteners and Other Hair Products and Incident Uterine Cancer.
Article in Journal of the National Cancer Institute, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Insights and limitations of endometrial cancer risk prediction models for clinical applicability: a systematic review.BMC cancer · 2025Pooled it
- Use of Chemical Hair Straighteners and Menstrual Disturbances.Journal of women's health (2002) · 2026Article
- Occupational exposures among hairdressers and the occurrence of hormone-related conditions.Occupational and environmental medicine · 2026Article
- Association between hair dye use and human cancers: A systematic review.JAAD international · 2026Review
- Use of hair straighteners and chemical relaxers and incidence of non-reproductive cancers.Journal of the National Cancer Institute · 2026Article
- Mapping, dynamism, thematic evolution of the scientific production on Make up or Beauty products and cancer: A scientometric study.Journal of education and health promotion · 2026Article
- Personal care products exposure patterns and prostate cancer: evidence from a case-control study in Mexico City.Journal of exposure science & environmental epidemiology · 2025Article
- Racial and ethnic differences in prenatal exposure to environmental phenols and parabens in the ECHO Cohort.Journal of exposure science & environmental epidemiology · 2025Article
- Evaluating personal care product use by Environmental Working Group hazard scores in relation to consumers' sociodemographic characteristics, purchasing behaviors, and product safety perceptions.Journal of exposure science & environmental epidemiology · 2025Article
- Tannin: An Insight into its Cosmeceutical Properties and Uses.Global challenges (Hoboken, NJ) · 2025Article
- The Power of Strategic Social Media Influencer Communication to Improve Black Women's Knowledge and Awareness of Environmental Endocrine-Disrupting Chemicals: Surveys of Instagram Users.Journal of medical Internet research · 2025Article
- Trends in Cancer Incidence and Mortality Rates in Early-Onset and Older-Onset Age Groups in the United States, 2010-2019.Cancer discovery · 2025Article
- Associations of personal care product use during pregnancy and the postpartum period with markers of postpartum glycemic control - Results from the ERGO Study.International journal of hygiene and environmental health · 2025Article
- The utility of silicone wristbands in characterizing exposure to parabens found in commercial lotions.The Science of the total environment · 2025Article
- Article
- Ultrasound-based versus immediate biopsy-based management of postmenopausal bleeding in non-Hispanic Black and non-Hispanic White individuals.Gynecologic oncology · 2025Article
- Chemicals of concern in select packaged hair relaxers available on the Kenyan market: an examination of ingredient labels and measurement of pH.Frontiers in public health · 2025Article
- Hair Straightener Use in Relation to Prevalent and Incident Fibroids in the Sister Study with a Focus on Black Women.Environmental health perspectives · 2025Article
- Hepatocellular carcinoma antibodies preferably identify nitro-oxidative-DNA lesions induced by 4-Chloro-orthophenylenediamine and DEANO.Scientific reports · 2024Article
- Asking Why Is Necessary to Address Health Disparities: A Critical Approach for Solution-Oriented Environmental Epidemiological Research.Environmental health perspectives · 2024Article
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Authors and funding
7 authors at 2 institutions in 1 country.
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Abstract
backgroundHair products may contain hazardous chemicals with endocrine-disrupting and carcinogenic properties. Previous studies have found hair product use to be associated with a higher risk of hormone-sensitive cancers including breast and ovarian cancer; however, to our knowledge, no previous study has investigated the relationship with uterine cancer.
methodsWe examined associations between hair product use and incident uterine cancer among 33 947 Sister Study participants aged 35-74 years who had a uterus at enrollment (2003-2009). In baseline questionnaires, participants in this large, racially and ethnically diverse prospective cohort self-reported their use of hair products in the prior 12 months, including hair dyes; straighteners, relaxers, or pressing products; and permanents or body waves. We estimated adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) to quantify associations between hair product use and uterine cancer using Cox proportional hazard models. All statistical tests were 2-sided.
resultsOver an average of 10.9 years of follow-up, 378 uterine cancer cases were identified. Ever vs never use of straightening products in the previous 12 months was associated with higher incident uterine cancer rates (HR = 1.80, 95% CI = 1.12 to 2.88). The association was stronger when comparing frequent use (>4 times in the past 12 months) vs never use (HR = 2.55, 95% CI = 1.46 to 4.45; Ptrend = .002). Use of other hair products, including dyes and permanents or body waves, was not associated with incident uterine cancer.
conclusionThese findings are the first epidemiologic evidence of association between use of straightening products and uterine cancer. More research is warranted to replicate our findings in other settings and to identify specific chemicals driving this observed association.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.