Evidence map›Paper›PMID 36244878›Full record

ReviewCytokine & growth factor reviews2022

The evolving epidemiology of monkeypox virus.

Heng Li, Hong Zhang, Ke Ding, Xiao-Hui Wang, Gui-Yin Sun, Zhen-Xing Liu, Yang Luo

Open access · greenAbstract readReview
In one paragraph

Review in Cytokine & growth factor reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 92 citations in OpenAlex.

  1. Article
  2. The aminoadamantane derivative 3F2 modulates monocyte and NK cell activation and restores immune mediators altered by Monkeypox virus stimuli.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Heng LiCenter of Smart Laboratory and Molecular Medicine, School of Medicine, Chongqing University, Chongqing 400044, PR China.
Hong ZhangDepartment of Clinical Laboratory, The Second Hospital of Shandong University, 250033 Jinan, Shandong, PR China.
Ke DingDepartment of Oncology, Jiangjin Hospital, Chongqing University, Chongqing 402260, PR China.
Xiao-Hui WangDepartment of Oncology, Jiangjin Hospital, Chongqing University, Chongqing 402260, PR China.
Gui-Yin SunDepartment of Oncology, Jiangjin Hospital, Chongqing University, Chongqing 402260, PR China. Electronic address: 228898511@qq.com.
Zhen-Xing LiuCenter of Smart Laboratory and Molecular Medicine, School of Medicine, Chongqing University, Chongqing 400044, PR China. Electronic address: zhenxingliu@cqu.edu.cn.
Yang LuoCenter of Smart Laboratory and Molecular Medicine, School of Medicine, Chongqing University, Chongqing 400044, PR China. Electronic address: luoy@cqu.edu.cn.
Chongqing University · CNJiangjin Central Hospital · CNSecond Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monkeypox, caused by the monkeypox virus (MPXV), is a zoonotic disease endemic mainly in West and Central Africa. As of 27 September 2022, human monkeypox has occurred in more than 100 countries (mostly in non-endemic regions) and caused over 66,000 confirmed cases, which differs from previous epidemics that mainly affected African countries. Due to the increasing number of confirmed cases worldwide, the World Health Organization (WHO) has declared the monkeypox outbreak as a Public Health Emergency of International Concern on July 23, 2022. The international outbreak of human monkeypox represents a novel route of transmission for MPXV, with genital lesions as the primary infection, and the emergence of monkeypox in the current outbreak is also new, as novel variants emerge. Clinical physicians and scientists should be aware of this emerging situation, which presents a different scenario from previous outbreaks. In this review, we will discuss the molecular virology, evasion of antiviral immunity, epidemiology, evolution, and detection of MPXV, as well as prophylaxis and treatment strategies for monkeypox. This review also emphasizes the integration of relevant epidemiological data with genomic surveillance data to obtain real-time data, which could formulate prevention and control measures to curb this outbreak.

Indexed as

Monkeypox virusMpox, MonkeypoxHumansPublic HealthEpidemiologyEvolutionMonkeypoxPublic healthZoonotic disease

Identifiers

PMID36244878
PMCPMC9547435
OpenAlexW4303649511

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.