ArticleArchives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists2023
Language Differences Among Individuals with Normal Cognition, Amnestic and Non-Amnestic MCI, and Alzheimer's Disease.
Article in Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Boston NamingTest performance in mild cognitive impairment: a meta-analysis.BMC neurology · 2026Pooled it
- Neuropsychological Diagnostic Tools in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.Aging and disease · 2025Pooled it
- Diagnostic Utility of Multi-Domain Language Measures Across the Alzheimer Disease Continuum.medRxiv : the preprint server for health sciences · 2026Article
- Altered dynamic functional connectivity of the language network associated with electronegative L5 in patients with mild cognitive impairment.GeroScience · 2026Article
- Increasing Educator Resources for Mild Cognitive Impairment and Dementia Using a Knowledge-to-Action Framework: The Development of DementiaBank Grand Rounds.American journal of speech-language pathology · 2026Article
- [Effects of a personalised, adapted computerised cognitive stimulation programme versus stimulating leisure activities in younger and older adults with mild or subjective cognitive impairment. Protocol for a randomised controlled trial].Anales del sistema sanitario de Navarra · 2025Article
- More than a Bundle? Developing Adaptive Guidance for Task Selection in an Online, Semantic-Based Cognitive Stimulation Program.Brain sciences · 2025Article
- Specificity of functional network connectivity during the AD prodromal phase in mild cognitive impairment.Frontiers in psychiatry · 2025Article
- Neuropsychiatric Symptoms Associated With Frontotemporal Atrophy in Older Adults Without Dementia.International journal of geriatric psychiatry · 2024Article
- Employing Verbal Divergent Thinking to Mitigate Cognitive Decline: Current State of Research and Reasons to Support Its Use.Geriatrics (Basel, Switzerland) · 2024Review
- Differentiation between Normal Cognition and Subjective Cognitive Decline in Older Adults Using Discrepancy Scores Derived from Neuropsychological Tests.Geriatrics (Basel, Switzerland) · 2024Article
- Cognitive trajectories preluding the onset of different dementia entities: a descriptive longitudinal study using the NACC database.Aging clinical and experimental research · 2024Article
- The Contribution of Functional Near-Infrared Spectroscopy (fNIRS) to the Study of Neurodegenerative Disorders: A Narrative Review.Diagnostics (Basel, Switzerland) · 2024Review
- Cognitive Performance and Incident Alzheimer's Dementia in Men Versus Women.The journal of prevention of Alzheimer's disease · 2024Article
- Exploring Verbal Fluency Strategies among Individuals with Normal Cognition, Amnestic and Non-Amnestic Mild Cognitive Impairment, and Alzheimer's Disease.Medicina (Kaunas, Lithuania) · 2023Article
- Article
- The efficacy of memory load on speech-based detection of Alzheimer's disease.Frontiers in aging neuroscience · 2023Article
- Qualitative Verbal Fluency Components as Prognostic Factors for Developing Alzheimer's Dementia and Mild Cognitive Impairment: Results from the Population-Based HELIAD Cohort.Medicina (Kaunas, Lithuania) · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveTo investigate differences in language performance among older adults with normal cognition (CN), mild cognitive impairment (MCI), and Alzheimer's disease (ad). Owing to the conflicting literature concerning MCI, discrepancies between amnestic (aMCI) and non-amnestic MCI (naMCI) were explored in greater detail.
methodThe study sample was drawn from the older (>64 years) HELIAD cohort. Language performance was assessed via semantic and phonemic fluency, confrontation naming, verbal comprehension, verbal repetition as well as a composite language index. Age, sex, and education adjusted general linear models were used to quantify potential pairwise differences in language performance.
resultsThe present analysis involved 1607 participants with CN, 146 with aMCI [46 single and 100 multi-domain aMCI], 92 with naMCI [41 single and 51 multi-domain naMCI], and 79 with ad. The mean age and education of our predominantly female (60%) participants were 73.82 (±5.43) and 7.98 (±4.93) years, respectively. MCI individuals performed between those with CN and ad, whereas participants with aMCI performed worse compared to those with naMCI, especially in the semantic fluency and verbal comprehension tasks. Discrepancies between the aMCI and naMCI groups were driven by the exquisitely poor performance of multi-domain aMCI subgroup.
conclusionsOverall, individuals could be hierarchically arranged in a continuum of language impairment with the CN individuals constituting the healthy reference and naMCI, aMCI, ad patients representing gradually declining classes in terms of language performance. Exploration of language performance via separation of single from multi-domain naMCI provided a potential explanation for the conflicting evidence of previous research.
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