Evidence map›Paper›PMID 36243982›Full record

ArticleNucleic acids research2023

AmyloGraph: a comprehensive database of amyloid-amyloid interactions.

Michał Burdukiewicz, Dominik Rafacz, Agnieszka Barbach, Katarzyna Hubicka, Laura Bąkała, Anna Lassota, Jakub Stecko, Natalia Szymańska, Jakub W Wojciechowski, Dominika Kozakiewicz and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Beyond bacteria: a multi-omics view of the gut-brain axis in Parkinson's disease.Frontiers in cellular and infection microbiology · 2026
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Experimental methods for studying amyloid cross-interactions.Protein science : a publication of the Protein Society · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Amyloid, Crohn's disease, and Alzheimer's disease - are they linked?Frontiers in cellular and infection microbiology · 2024
    Review
  12. Article
  13. How Big Is the Yeast Prion Universe?International journal of molecular sciences · 2023
    Review
  14. Article
  15. Testing Antimicrobial Properties of Selected Short Amyloids.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 3 countries.

Michał BurdukiewiczInstitute of Biotechnology and Biomedicine, Autonomous University of Barcelona, Campus Universitat Autònoma de Barcelona Plaça Cívica Bellaterra, s/n, 08193 Cerdanyola del Vallès, Barcelona, Spain.ORCID 0000-0001-8926-582X
Dominik RafaczFaculty of Mathematics and Information Science, Warsaw University of Technology, Koszykowa 75, 00-662 Warsaw, Poland.ORCID 0000-0003-0925-1909
Agnieszka BarbachDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0002-3499-8126
Katarzyna HubickaDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.
Laura BąkałaFaculty of Mathematics and Information Science, Warsaw University of Technology, Koszykowa 75, 00-662 Warsaw, Poland.ORCID 0000-0002-3213-2484
Anna LassotaSchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.ORCID 0000-0001-6073-8603
Jakub SteckoFaculty of Medicine, Wrocław Medical University, Ludwika Pasteura 1, 50-367 Wrocław, Poland.ORCID 0000-0002-1427-3742
Natalia SzymańskaFaculty of Medicine, Wrocław Medical University, Ludwika Pasteura 1, 50-367 Wrocław, Poland.
Jakub W WojciechowskiDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0001-5289-653X
Dominika KozakiewiczLaboratory of Microbiome Immunobiology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, 53-114 Wrocław, Poland.ORCID 0000-0001-6659-257X
Natalia SzulcDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0003-2951-1827
Jarosław ChilimoniukDepartment of Genomics, Faculty of Biotechnology, University of Wrocław, Fryderyka Joliot-Curie 14a, 50-383 Wrocław, Poland.ORCID 0000-0001-5467-018X
Izabela JęśkowiakDepartment of Pharmacology, Wroclaw Medical University, Mikulicza-Radeckiego 2, 50-345 Wrocław, Poland.ORCID 0000-0002-8829-4482
Marlena Gąsior-GłogowskaDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0002-7835-7523
Małgorzata KotulskaDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0002-2015-5339
Wrocław University of Science and Technology · PLWroclaw Medical University · PLWarsaw University of Technology · PLLudwik Hirszfeld Institute of Immunology and Experimental Therapy · PLUniversitat Autònoma de Barcelona · ESUniversity of Birmingham · GBUniversity of Wrocław · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Information about the impact of interactions between amyloid proteins on their fibrillization propensity is scattered among many experimental articles and presented in unstructured form. We manually curated information located in almost 200 publications (selected out of 562 initially considered), obtaining details of 883 experimentally studied interactions between 46 amyloid proteins or peptides. We also proposed a novel standardized terminology for the description of amyloid-amyloid interactions, which is included in our database, covering all currently known types of such a cross-talk, including inhibition of fibrillization, cross-seeding and other phenomena. The new approach allows for more specific studies on amyloids and their interactions, by providing very well-defined data. AmyloGraph, an online database presenting information on amyloid-amyloid interactions, is available at (http://AmyloGraph.com/). Its functionalities are also accessible as the R package (https://github.com/KotulskaLab/AmyloGraph). AmyloGraph is the only publicly available repository for experimentally determined amyloid-amyloid interactions.

Indexed as

AmyloidAmyloidogenic ProteinsDatabases, ProteinPeptidesAmyloidAmyloidogenic ProteinsPeptides

Identifiers

PMID36243982
PMCPMC9825533
OpenAlexW4306353210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.