Evidence map›Paper›PMID 36243808›Full record

ArticleInternational journal of colorectal disease2022

C-reactive protein values after surgery for inflammatory bowel disease: is it still a good marker for intra-abdominal complication? A retrospective cohort study of 347 procedures : CRP after inflammatory bowel disease surgery.

Gaspard Bouteloup, Jérémie H Lefevre, Alexandre Challine, Thibault Voron, Lauren O'Connell, Clotilde Debove, Najim Chafai, Yann Parc, Saint-Antoine IBD Network

Abstract read
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In one paragraph

Article in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
  3. C-reactive protein and digestive pathologies: A narrative review for daily clinical use.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Surgical Outcomes in 62 Patients with Ulcerative Colitis: A Retrospective, Single-Center Study from Poland.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Gaspard BouteloupDepartment of Digestive Surgery, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, 184 rue du faubourg Saint-Antoine, F75012, Paris, France.
Jérémie H LefevreDepartment of Digestive Surgery, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, 184 rue du faubourg Saint-Antoine, F75012, Paris, France. jeremie.lefevre@aphp.fr.ORCID https://orcid.org/0000-0001-7601-7464
Alexandre ChallineDepartment of Digestive Surgery, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, 184 rue du faubourg Saint-Antoine, F75012, Paris, France.
Thibault VoronDepartment of Digestive Surgery, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, 184 rue du faubourg Saint-Antoine, F75012, Paris, France.
Lauren O'ConnellDepartment of Colorectal Surgery, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
Clotilde DeboveDepartment of Digestive Surgery, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, 184 rue du faubourg Saint-Antoine, F75012, Paris, France.
Najim ChafaiDepartment of Digestive Surgery, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, 184 rue du faubourg Saint-Antoine, F75012, Paris, France.
Yann ParcDepartment of Digestive Surgery, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, 184 rue du faubourg Saint-Antoine, F75012, Paris, France.
Saint-Antoine IBD Network
Sorbonne Université · FRSt. Vincent's University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeC-reactive protein (CRP) is a useful predictive test to early detect abdominal complication after colorectal surgery. Inflammatory bowel disease (IBD) is responsible for chronic inflammation and abnormal basal CRP that could influence the interest of its management after abdominal surgery. The aim of this study is to evaluate CRP as an indicator of postoperative complication in a specific IBD population.

methodsRetrospective study of patients undergoing ileocolic resection or ileal pouch-anal anastomosis for IBD between 2012 and 2019.

resultsIleocolic resection represents 242 patients and ileal pouch-anal anastomosis 105 patients. CRP was significantly higher at an early (105.2 ± 56.0 vs 128.1 ± 69.8; p = 0.008) and late stage (112.9 ± 72.8 vs 185.3 ± 111.5; p < 0.0001) for patients having an intra-abdominal complication. A BMI > 25 kg/m

conclusionCRP is a useful predictive marker to detect abdominal complication after surgery in IBD population. Measurement of CRP can help to reduce hospitalization stay and orientate towards complementary examinations.

Indexed as

C-Reactive ProteinInflammatory Bowel DiseasesAnastomotic LeakBiomarkersColectomyHumansPostoperative ComplicationsRetrospective StudiesBiomarkersC-Reactive ProteinC-reactive proteinIleal pouchIleocecal resectionMorbidity

Identifiers

PMID36243808
OpenAlexW4306315900

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.