Evidence map›Paper›PMID 36243752›Full record

ArticleRespiratory research2022

Expiratory high-frequency percussive ventilation: a novel concept for improving gas exchange.

Ferenc Peták, Gergely H Fodor, Álmos Schranc, Roberta Südy, Ádám L Balogh, Barna Babik, André Dos Santos Rocha, Sam Bayat, Davide Bizzotto, Raffaele L Dellacà and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Ferenc PetákDepartment of Medical Physics and Informatics, University of Szeged, 9, Korányi fasor, Szeged, 6720, Hungary. petak.ferenc@med.u-szeged.hu.
Gergely H FodorDepartment of Medical Physics and Informatics, University of Szeged, 9, Korányi fasor, Szeged, 6720, Hungary.
Álmos SchrancDepartment of Medical Physics and Informatics, University of Szeged, 9, Korányi fasor, Szeged, 6720, Hungary.
Roberta SüdyDepartment of Medical Physics and Informatics, University of Szeged, 9, Korányi fasor, Szeged, 6720, Hungary.
Ádám L BaloghUnit for Anaesthesiological Investigations, Department of Acute Medicine, University of Geneva, Geneva, Switzerland.
Barna BabikDepartment of Anaesthesiology and Intensive Therapy, University of Szeged, Szeged, Hungary.
André Dos Santos RochaUnit for Anaesthesiological Investigations, Department of Acute Medicine, University of Geneva, Geneva, Switzerland.
Sam BayatUniv. Grenoble Alpes, Inserm UA07 STROBE Laboratory & Department of Pneumology and Clinical Physiology, Grenoble University Hospital, Grenoble, France.
Davide BizzottoDipartimento Di Elettronica, Informazione E Bioingegneria, Politecnico di Milano, Milan, Italy.
Raffaele L DellacàDipartimento Di Elettronica, Informazione E Bioingegneria, Politecnico di Milano, Milan, Italy.
Walid HabreUnit for Anaesthesiological Investigations, Department of Acute Medicine, University of Geneva, Geneva, Switzerland.
University of Szeged · HUPolitecnico di Milano · ITUniversity of Geneva · CHCentre Hospitalier Universitaire de Grenoble · FRUniversity Hospital of Geneva · CH

Funding

Hungarian Science Foundation OTKA-NKFIH K138032
6 · The paper itself

Abstract

backgroundAlthough high-frequency percussive ventilation (HFPV) improves gas exchange, concerns remain about tissue overdistension caused by the oscillations and consequent lung damage. We compared a modified percussive ventilation modality created by superimposing high-frequency oscillations to the conventional ventilation waveform during expiration only (eHFPV) with conventional mechanical ventilation (CMV) and standard HFPV.

methodsHypoxia and hypercapnia were induced by decreasing the frequency of CMV in New Zealand White rabbits (n = 10). Following steady-state CMV periods, percussive modalities with oscillations randomly introduced to the entire breathing cycle (HFPV) or to the expiratory phase alone (eHFPV) with varying amplitudes (2 or 4 cmH

resultsThe use of eHFPV with 5 Hz superimposed oscillation frequency and an amplitude of 4 cmH

conclusionsThese findings demonstrated improved gas exchange using eHFPV as a novel mechanical ventilation modality that combines the benefits of conventional and small-amplitude high-frequency oscillatory ventilation, owing to improved longitudinal gas transport rather than increased lung surface area available for gas exchange.

Indexed as

Cytomegalovirus InfectionsHigh-Frequency VentilationAnimalsCarbon DioxideOxygenPulmonary Gas ExchangeRabbitsRespiration, ArtificialCarbon DioxideOxygenAlveolar recruitmentBlood gasCapnographyGas exchangeLung ventilation

Identifiers

PMID36243752
PMCPMC9569091
OpenAlexW4306292120

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.