ArticleAdvances in therapy2022
The Rise of Prescription Digital Therapeutics in Behavioral Health.
Article in Advances in therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Digital Therapeutics for People with Schizophrenia Spectrum Disorders: A Systematic Literature Review of Their Effect on Symptoms and Functioning.Schizophrenia bulletin · 2026Pooled it
- Preliminary Efficacy of a Digital Intervention for Adolescent Depression: Randomized Controlled Trial.Journal of medical Internet research · 2024Trial
- Article
- Comparing mental health professionals' willingness to use digital therapeutics: a cross-national survey in South Korea and Germany.BMC health services research · 2026Article
- Innovations to improve outcomes and uptake of psychotherapies for mental disorders: a state-of-the-art review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Privacy policies for FDA-authorized or FDA-recognized digital therapeutics impose high digital health literacy demands: a cross-sectional analysis.Frontiers in public health · 2026Article
- Integrating digital therapeutics for patients with mental illness into clinical practice: perspectives for US healthcare professionals.Frontiers in public health · 2026Review
- Effectiveness of digital interventions for eight mental disorders: A meta-analytic synthesis.Internet interventions · 2025Review
- Current Status and Future Directions in the Development of Digital Therapeutic Interventions for Neurodevelopmental Disorders.Clinical pharmacology and therapeutics · 2025Review
- Therapeutic Evaluation and Utilization Analysis of Mental Health Prescription Digital Therapeutics Within the Current Regulatory Landscape.Pharmacy (Basel, Switzerland) · 2025Review
- Development and Validation of the Digital Sensitivity Scale for Adults: Cross-Sectional Observational Study.Journal of medical Internet research · 2025Observational
- Download to heal: navigating the pixelated path of digital therapeutics in psychiatric care.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Review
- Assessing rural populations' barriers to mental healthcare and perceptions towards prescription digital therapeutics: a cross-sectional survey.Frontiers in digital health · 2025Article
- Clinical Efficacy of Application-Linked Stretching Ball as Digital Therapeutics in Plantar Fasciitis.Journal of clinical medicine · 2024Article
- Development and Evaluation of a Digital App for Patient Self-Management of Opioid Use Disorder: Usability, Acceptability, and Utility Study.JMIR formative research · 2024Article
- Adoption of Digital Therapeutics in Europe.Therapeutics and clinical risk management · 2024Review
- From palm to practice: prescription digital therapeutics for mental and brain health at the National Institutes of Health.Frontiers in psychiatry · 2024Article
- Mapping Factors That Affect the Uptake of Digital Therapeutics Within Health Systems: Scoping Review.Journal of medical Internet research · 2023Article
- Digital Therapeutics (DTx) Expand Multimodal Treatment Options for Chronic Low Back Pain: The Nexus of Precision Medicine, Patient Education, and Public Health.Healthcare (Basel, Switzerland) · 2023Article
- The State of Digital Biomarkers in Mental Health.Digital biomarkersArticle
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Medicine is evolving to incorporate digital technologies of all kinds-technologies that may improve patient health, reduce clinician workload, lower costs, reduce health disparities, and expand access to needed treatments. Prescription digital therapeutics (PDTs) are an emerging technology with particular potential. These are software-based treatments delivered on mobile devices that address the behavioral dimensions of many diseases and conditions. Unlike health and wellness apps, PDTs are rigorously evaluated for safety and effectiveness and are authorized by the US Food and Drug Administration (FDA). Nine PDTs are currently authorized to treat conditions such as substance use disorders, attention-deficit disorder, and chronic insomnia. The findings reported in two recent research papers published by Advances in Therapy related to use of PDTs for substance use disorder and opioid use disorder provide real-world evidence of clinical and cost effectiveness, strengthening the evidence base for these technologies and suggesting a role for these technologies in the efforts to help patients recover from these often-chronic and deadly conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.