Trial reportAging clinical and experimental research2022
The challenge of recruiting multimorbid older patients identified in a hospital database to a randomised controlled trial.
Trial report in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Effect of home-based comprehensive geriatric assessment on hospital days in multimorbid older adults: a randomized controlled trial (the GerMoT trial).European geriatric medicine · 2026Trial
- Could the Geriatric Mobile Team trial (GerMoT) inclusion criteria be a pragmatic approach to identifying older adults who may be a relevant target group for integrated care interventions?European geriatric medicine · 2026Article
- Recalibrating Resting Energy Expenditure Prediction Equations in Asian Older Adults with Multimorbidity.Nutrients · 2026Article
- Why are older adults living with the complexity of multiple long-term conditions, frailty and a recent deterioration in health under-served by research? A narrative synthesis review of the literature.Journal of frailty, sarcopenia and falls · 2023Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundResearch involving multimorbid older patients is gaining momentum. However, little is known about how to plan a randomised controlled trial (RCT) involving this group of patients. An evidence-based approach to the challenges of a recruitment process could guide researchers and help prevent underpowered trials.
aimTo define the number of multimorbid older patients that need to be identified and the number of eligible patients that need to be invited to achieve the desired recruitment number to a RCT.
methodWe used recruitment data from the GerMoT trial, a RCT comparing proactive outpatient care based on Comprehensive Geriatric Assessment with usual care. Multimorbid older patients with high healthcare utilisation were recruited to the trial.
resultsOf the 1212 patients identified in a database as meeting the inclusion criteria 838 (70%) could be invited to participate in the trial. The rest could not be invited for a variety of reasons; 162 had moved out of area or into nursing homes and 86 had died before they could be contacted. 113 could not be reached. 450 (54%) of the invited patients agreed to participate.
conclusionsIn our study, we have shown that it is possible to achieve a good consent rate despite older participants with multimorbidity. This can be used when planning an RCT for this patient group, who are often excluded from clinical trials. Our results are specific to a context that provides similar abilities to identify and recruit patients as can be seen in Sweden.
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