Evidence map›Paper›PMID 36242699›Full record

ReviewReviews in endocrine & metabolic disorders2023

Endocrine responses of the stress system to different types of exercise.

Nikolaos Athanasiou, Gregory C Bogdanis, George Mastorakos

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In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nikolaos AthanasiouUnit of Endocrinology, Diabetes mellitus and Metabolism, School of medicine, ARETAIEION hospital, National and Kapodistrian University of Athens, Neofytou Vamva str 10674, Athens, Greece.ORCID 0000-0003-2413-8576
Gregory C BogdanisSchool of Physical Education and Sports Science, National and Kapodistrian University of Athens, 17237, Dafne, Greece.ORCID 0000-0003-3382-0438
George MastorakosUnit of Endocrinology, Diabetes mellitus and Metabolism, School of medicine, ARETAIEION hospital, National and Kapodistrian University of Athens, Neofytou Vamva str 10674, Athens, Greece. mastorakg@gmail.com.ORCID 0000-0002-1929-3275

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity is an important part of human lifestyle although a large percentage of the population remains sedentary. Exercise represents a stress paradigm in which many regulatory endocrine systems are involved to achieve homeostasis. These endocrine adaptive responses may be either beneficial or harmful in case they exceed a certain threshold. The aim of this review is to examine the adaptive endocrine responses of hypothalamic-pituitary-adrenal axis (HPA), catecholamines, cytokines, growth hormone (GH) and prolactin (PRL) to a single bout or regular exercise of three distinct types of exercise, namely endurance, high-intensity interval (HIIE) and resistance exercise. In summary, a single bout of endurance exercise induces cortisol increase, while regular endurance exercise-induced activation of the HPA axis results to relatively increased basal cortisolemia; single bout or regular exercise induce similar GH peak responses; regular HIIE training lowers basal cortisol concentrations, while catecholamine response is reduced in regular HIIE compared with a single bout of HIIE. HPA axis response to resistance exercise depends on the intensity and volume of the exercise. A single bout of resistance exercise is characterized by mild HPA axis stimulation while regular resistance training in elderly results in attenuated inflammatory response and decreased resting cytokine concentrations. In conclusion, it is important to consider which type of exercise and what threshold is suitable for different target groups of exercising people. This approach intends to suggest types of exercise appropriate for different target groups in health and disease and subsequently to introduce them as medical prescription models.

Indexed as

Human Growth HormoneHypothalamo-Hypophyseal SystemAgedCatecholaminesCytokinesEndocrine SystemExerciseGrowth HormoneHumansHydrocortisonePituitary-Adrenal SystemCatecholaminesCytokinesGrowth HormoneHuman Growth HormoneHydrocortisoneCatecholaminesCortisolExerciseGHHPAIL-6

Identifiers

PMID36242699
PMCPMC10023776

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.