Evidence map›Paper›PMID 36242529›Full record

SynthesisObstetrical & gynecological survey2022

Effect of Intrapartum Maternal Hemoglobin on Mode of Delivery and Short-Term Neonatal Outcome: A Systematic Review.

Julia Sandra Smith, Lauren Maria Bullens, Marieke Beatrijs van der Hout-van der Jagt, Pieter Jurjen van Runnard Heimel, Swan Gied Oei

Abstract readSystematic Review
In one paragraph

Synthesis in Obstetrical & gynecological survey, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia Sandra SmithMedical Student, Faculty of Health, Medicine, and Life Sciences, Maastricht University, Maastricht, the Netherlands.
Lauren Maria BullensGynecologist, Department of Obstetrics and Gynecology, Streekziekenhuis Koningin Beatrix, Winterswijk, the Netherlands.
Marieke Beatrijs van der Hout-van der JagtClinical Researcher, Department of Gynecology and Obstetrics, Màxima Medical Center, Veldhoven, the Netherlands; Biomedical Engineer, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
Pieter Jurjen van Runnard HeimelGynecologist-Perinatologist, Department of Gynecology and Obstetrics, Màxima Medical Center, Veldhoven, the Netherlands.
Swan Gied OeiGynecologist-Perinatologist, Department of Gynecology and Obstetrics, Màxima Medical Center, Veldhoven, the Netherlands; Professor, Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Maternal anemia in pregnancy is a common condition worldwide and is considered a risk factor for adverse neonatal and maternal outcome. Also high hemoglobin (Hb) levels are associated with adverse pregnancy outcomes. However, studies regarding the influence of intrapartum maternal Hb on mode of delivery and short-term neonatal outcome are limited and contradicting. Objective: The aim of this study was to provide an overview of current evidence regarding associations between intrapartum maternal Hb levels and mode of delivery and short-term neonatal outcome. In addition, we propose directions for future research. Evidence Acquisition: We systematically searched the electronic PubMed, EMBASE, and Cochrane databases for studies on maternal Hb levels and mode of delivery maternal and short-term neonatal outcome until January 2021. Eligible articles and their references were independently reviewed by 2 authors. Assessment was based on methodological quality and study results. Results: We included 14 studies that evaluated the level of maternal pH in relation to clinical outcome, 6 studies on mode of delivery, 10 studies on Apgar score, 1 study on fetal distress, 2 studies on neonatal intensive care unit admission, 1 study on umbilical cord pH, and 5 studies on perinatal mortality. Conclusions and Relevance: We found a trend toward an increased risk of cesarean delivery in anemic woman. Concerning the short-term neonatal outcomes, the evidence is conflicting, and included studies are too heterogenic to compare. Furthermore, various studies indicated a relation between high Hb levels and increased perinatal mortality. Therefore, we especially recommend attention to elevated Hb levels.

Indexed as

Cesarean SectionFetal DistressFemaleHemoglobinsHumansInfant, NewbornPregnancyPregnancy OutcomeHemoglobins

Identifiers

PMID36242529
PMCPMC9561235

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.