ArticleTropical medicine and health2022
Neurobrucellosis: report of 54 cases.
Article in Tropical medicine and health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Isolated oculomotor nerve palsy as the sole presenting feature of neurobrucellosis: a case report.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Review
- The impact of previous brucellosis treatment on the clinical course of neurobrucellosis: a multicentre retrospective study.BMC infectious diseases · 2026Article
- Concurrent neurobrucellosis and central nervous system aspergillosis in an immunocompetent host: a case report.Journal of medical case reports · 2026Article
- Development and internal validation of a nomogram for predicting neurobrucellosis in hospitalized patients with brucellosis: a single-center retrospective study.Frontiers in cellular and infection microbiology · 2026Article
- Chronic Headache and Visual Field Loss: Manifestations in a Patient With ChronicCase reports in infectious diseases · 2026Article
- Human herpesvirus type 4 combined with Brucella abortus meningitis case report.BMC infectious diseases · 2025Article
- A rare case report of neuro-brucellosis with concurrence of depression, visual impairment, bilateral sensorineural hearing loss, and paraplegia.PLoS neglected tropical diseases · 2025Article
- Insidious meningitis induced by brucellosis: a case report.Journal of medical case reports · 2025Article
- Article
- Acute psychosis due to brucellosis.Indian journal of psychiatry · 2025Article
- Neurobrucellosis: a retrospective cohort of 106 patients.Tropical medicine and health · 2025Article
- Neurobrucellosis Presenting as a Conglomerate Space-Occupying Lesion.Annals of Indian Academy of Neurology · 2025Article
- Acute Transverse Myelitis as an Uncommon Presentation of Neurobrucellosis: A Case Report.Clinical case reports · 2025Article
- Neurobrucellosis presenting as acute stroke with brain abscesses: a case report.American journal of neurodegenerative disease · 2025Article
- Article
- Article
- Molecular diagnostics in cerebrospinal fluid for the diagnosis of central nervous system infections.Clinical microbiology reviews · 2024Review
- Seronegative brucella meningitis diagnosed by CSF PCR: report on seven cases.BMC infectious diseases · 2024Article
- Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundBrucellosis is among the most widespread zoonotic diseases worldwide. Although rare, nervous system involvement due to Brucella infection is a major diagnostic challenge in endemic regions. PATIENTS AND
methodsThis study was a cross-sectional investigation of hospitalized adults with neurobrucellosis from March 2007 to February 2017. We described the clinical characteristics, radiographical and laboratory features, and clinical outcomes of patients with neurobrucellosis.
resultsFifty-four patients with neurobrucellosis were included. The median age was 35 (interquartile range, 25-50) years, and 32 (59%) cases were male. Thirty-four (63%) patients were stockmen or shepherds. The most common clinical manifestations were fever in 49 (91%) cases, headache in 47 (87%), decreased consciousness in 12 (22%), and seizures in 6 (11%). Meningeal signs were detected in 36 (67%) cases. Brucella species were isolated in five cases from blood or cerebrospinal fluid (CSF). The median of CSF leukocytes was 75 per µL, CSF protein 83 mg/dL, and CSF glucose 39 mg/dL. Only two cases had severe hypoglycorrhachia and one CSF protein ≥ 500 mg/dL. No patient died during hospitalization.
conclusionsThe symptoms of neurobrucellosis could be mild and nonspecific and the classic triad of meningitis is uncommon. Mild CSF pleocytosis of fewer than 50 leukocytes per microliter of CSF was common but severe hyperproteinorrhachia and severe hypoglycorrhachia were rare in neurobrucellosis. Differentiation between neurobrucellosis and systemic brucellosis is important, because more prolonged treatment is indicated for neurobrucellosis, and it could be associated with a broad spectrum of complications that require close follow-up.
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