ArticleBMC oral health2022
Estimated projection of oral cavity and oropharyngeal cancer deaths in Spain to 2044.
Article in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 23 citations in OpenAlex.
- Changes in gingival cancer: burden of hospitalization and epidemiological evolution from 2001 to 2023 in Spain. a novel approach using hospital activity registry data.BMC oral health · 2026Article
- Geographic inequalities and gender-specific trends in oropharyngeal cancer mortality in Spain.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Sentinel Lymph Node Biopsy for Early-Stage Oral Cavity Cancer: Analysis of Diagnostic Accuracy and False-Negative Cases.Journal of clinical medicine · 2026Article
- Mortality trends for oral and oropharyngeal cancer in Latin American and Caribbean countries, 1997 to 2020.BMC oral health · 2026Observational
- Oral and Oropharyngeal Cancer Mortality in Brazil: Estimates and Projections up to 2042.Community dentistry and oral epidemiology · 2025Article
- Increasing incidence, prevalence, and mortality of lip and oral cavity cancer in adults aged 70 and older globally: findings from GBD 2021.World journal of surgical oncology · 2025Article
- Global burden of head and neck cancer: Epidemiological transitions, inequities, and projections to 2050.Frontiers in oncology · 2025Article
- Recent knowledge on squamous cell carcinoma of the oral cavity: Contributing factors, underlying molecular pathways, and current attitudes in the therapeutic approaches.International journal of molecular and cellular medicine · 2025Review
- Complex IIa formation and ABC transporters determine sensitivity of OSCC to Smac mimetics.Cell death & disease · 2024Article
- Pancreatic stellate cells and the interleukin family: Linking fibrosis and immunity to pancreatic ductal adenocarcinoma (Review).Molecular medicine reports · 2024Review
- Impact of Treatment on Quality of Life in Oropharyngeal Cancer Survivors: A 3-Year Prospective Study.Cancers · 2024Article
- Eugenol as a potential adjuvant therapy for gingival squamous cell carcinoma.Scientific reports · 2024Article
- Public Awareness on Oral Cancer: A Population- Based Study in Asturias.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Are sex and gender considered in head and neck cancer clinical studies?NPJ precision oncology · 2023Article
- Article
- Projecting the burden of dental caries and periodontal diseases among the adult population in the United Kingdom using a multi-state population model.Frontiers in public health · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOral cavity cancer (OCC) and oropharyngeal cancer (OPC) are two common malignancies whose mortality is worryingly increasing worldwide. However, few studies have estimated the mortality trends for these cancers in the coming years. This study analysed the mortality rates for OCC and OPC observed between 1980 and 2019 to generate a predictive model for the next 25 years in Spain.
methodsMid-year population data and death certificates for the period 1980-2019 were obtained from the Spanish National Institute of Statistics. The Nordpred program (Norwegian Cancer Registry, Oslo, Norway) was used to calculate adjusted mortality rates as well as estimated mortality projections with an age-period-cohort model for the period 2020-2044.
resultsThe specific mortality rate per 100,000 inhabitants for OCC decreased from 2.36 (1980-1984) to 2.17 (2015-2019) and is expected to decline to 1.68 (2040-2044), particularly in males. For OPC, mortality rates rose from 0.67 (1980-1984) to 1.23 (2015-2019) and are projected to drop to 0.71 (2040-2044). In the group of females > 65 years predictions showed rising mortality rates for both OCC and OPC. The predictive model projects more deaths in females than in males for OCC in the period 2040-2044, while deaths for OPC will decrease in males and gradually increase in females.
conclusionsAlthough OCC mortality rates have been found to decrease in males in the last observed decades, there is still room to improve them in females > 65 years in the future by promoting campaigns against smoking and alcohol consumption. OPC mortality will become a growing health problem. Vaccination campaigns for the prevention of human papillomavirus-associated cancers may have a long-term impact on the mortality of these cancers, which should be evaluated in upcoming studies. CLINICAL RELEVANCE: Our findings highlighted the importance of closely monitoring OCC and OPC mortality rates in the coming years by age group and sex, and the need to continue preventive measures against the main known risk factors, such as tobacco, alcohol, and human papillomavirus infection.
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