ArticleBMC musculoskeletal disorders2022
Mapping of lumbar multifidus stiffness Quantification in ankylosing spondylitis with shear-wave elastography.
Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- The association between trunk muscle stiffness measured using shear wave elastography and VF in women aged 60 and over: a cross-sectional study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Article
- Vertebral Ankylosis Is Associated with Reduced Cervical Extensor Muscle Bulk and Increased Fatty Degeneration.Journal of clinical medicine · 2025Article
- Analyzing the Usage of Shear-Wave Elastography in Evaluating Ankylosing Spondylitis: A Literature Review.Cureus · 2025Review
- Diagnostic Accuracy of Shear Wave Elastography Versus Ultrasound in Plantar Fasciitis Among Patients with and Without Ankylosing Spondylitis.Diagnostics (Basel, Switzerland) · 2025Article
- Ultrasound elastography of back muscle biomechanical properties: a systematic review and meta-analysis of current methods.Insights into imaging · 2024Review
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLower back pain and stiffness are the typical symptoms of ankylosing spondylitis (AS). In this study, muscle mass was assessed by muscle density, mechanical elasticity, and area. We investigated the characteristics of lumbar paraspinal-muscle (PSM) mass using muscle ultrasound shear-wave elastography (SWE), as well as the validity of this method for identifying patients with AS.
methodsWe recruited a representative cohort of 30 AS patients, and 27 healthy volunteers who were age- and sex-matched to the patient study group, investigated the Young's modulus (YM), cross-sectional area (CSA) and thickness of lumbar multifidus (LM) muscle using SWE. This study did not need to be randomized. Data were collected at the department of ultrasonography of Guangdong Provincial Hospital of Chinese Medicine. We analyzed the data using SPSS version 18.0 (IBM Corp, Armonk, NY, USA). Normal distribution was evaluated by the Shapiro-Wilk test and Q-Q plots. Demographic and baseline data will be analyzed with standard descriptive statistics. Data will be presented as the mean ± standard deviation (SD). Non-normally distributed data are presented as medians with interquartile ranges (IQR).
resultsYoung's modulus (YM) of SWE in AS patients was significantly higher than that in volunteers. Percentage change in lumbar multifidus (LM) muscle cross-sectional area (CSA) and thickness were significantly lower in AS patients than in healthy volunteers on the left side of the body. Correlation analysis showed a positive correlation between percentage change in CSA and thickness in both volunteers and AS patients. In AS patients, YM was negatively correlated with percentage change of CSA and thickness on the right side, while increased disease duration in AS was associated with increased YM on the left.
conclusionAS patients showed reductions in LM muscle mass and function as the disease progressed, SWE could reflect these changes well.
trial registrationChinese Clinical Trial Registry, ChiCTR2000031476. Registered 02/04/2020. http://www.chictr.org.cn/index.aspx .
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