ArticleScientific reports2022
Trend in neuraxial morphine use and postoperative analgesia after cesarean delivery in Japan from 2005 to 2020.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of intravenous dexamethasone on postoperative pain after caesarean delivery under spinal anaesthesia with an intrathecal long-acting opioid: a systematic review and meta-analysis.Journal of anesthesia · 2023Pooled it
- Determination of the ED90 for Epidural Hydromorphone and Morphine for Postoperative Pain Using a Biased-Coin Up-and-Down Sequential Design After Elective Cesarean Delivery.Drug design, development and therapy · 2026Trial
- Analgesic Efficacy and Safety of Intrathecal Morphine in Surgical Patients: A Narrative Review.Cureus · 2026Review
- The impact of frailty on postoperative complications and resource utilization in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI).Nagoya journal of medical science · 2026Article
- Article
- Preventive effects of perioperative drug injection on postoperative delirium after hip fracture surgery: a systematic review and meta-analysis.American journal of translational research · 2025Review
- Anesthesia practice for Cesarean delivery in Japan: a retrospective cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing rate of cesarean deliveries warrants obstetric anesthesiologists to deliver high-quality post-cesarean delivery analgesia. The aim of this study was to evaluate the temporal trends in the use of neuraxial morphine for cesarean deliveries and to describe the current postoperative analgesia practices. A retrospective cohort study using nationwide health insurance claims databases was conducted from 2005 to 2020 in Japan. Pregnant women who had undergone cesarean deliveries were included. The annual rate of neuraxial morphine use was extracted and analyzed. Additionally, we explored the patient- and facility-level factors associated with neuraxial morphine use through a multilevel logistic regression analysis. The cohort included 65,208 cesarean delivery cases from 2275 institutions. The prevalence of neuraxial morphine use was 16.0% (95% confidence interval [CI], 15.8-16.3) in the overall cohort. Intrathecal morphine was used in 20.6% (95% CI, 20.2-21.0) of spinal anesthesia cases. The trend in neuraxial morphine use steadily increased from 2005 to 2020. The significant predictors of neuraxial morphine use included spinal anesthesia, recent surgery, large medical facilities, and academic hospitals. Variations in the utilization of postoperative analgesia were observed. Our study described the current trend of neuraxial morphine use and the variation in postoperative analgesia practice in Japan.
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