Evidence map›Paper›PMID 36241747›Full record

ArticleSurgical endoscopy2023

Outcome of endoscopic vacuum therapy for duodenal perforation.

Mickael Chevallay, Florian Lorenz, Philippe Bichard, Jean-Louis Frossard, Thomas Schmidt, Tobias Goeser, Christiane Josephine Bruns, Stefan P Mönig, Seung-Hun Chon

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Endoscopic vacuum therapy.iGIE : innovation, investigation and insights · 2024
    Article
  5. Article
  6. Endoscopic vacuum therapy in the upper gastrointestinal tract.Frontiers in gastroenterology (Lausanne, Switzerland) · 2024
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Mickael Chevallay *Department of Visceral Surgery, Geneva University Hospitals, Geneva, Switzerland.
Florian Lorenz *Department of Gastroenterology and Hepatology, University Hospital of Cologne, Cologne, Germany.
Philippe BichardDepartment of Gastroenterology and Hepatology, Geneva University Hospital, Geneva, Switzerland.
Jean-Louis FrossardDepartment of Gastroenterology and Hepatology, Geneva University Hospital, Geneva, Switzerland.
Thomas SchmidtDepartment of General, Visceral, Cancer, and Transplantat Surgery, University Hospital of Cologne, Cologne, Germany.
Tobias GoeserDepartment of General, Visceral, Cancer, and Transplantat Surgery, University Hospital of Cologne, Cologne, Germany.
Christiane Josephine BrunsDepartment of General, Visceral, Cancer, and Transplantat Surgery, University Hospital of Cologne, Cologne, Germany.
Stefan P MönigDepartment of Visceral Surgery, Geneva University Hospitals, Geneva, Switzerland.
Seung-Hun ChonDepartment of Gastroenterology and Hepatology, University Hospital of Cologne, Cologne, Germany. seung-hun.chon@uk-koeln.de.ORCID http://orcid.org/0000-0002-8923-6428
University Hospital Cologne · DEUniversity Hospital of Geneva · CHUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuodenal defects are complex clinical situations, and their management is challenging and associated with high mortality. Besides surgery, endoscopic treatment options exist, but the size and location of the perforation can limit their application. We present a retrospective study, demonstrating a successful application of endoscopic vacuum therapy (EVT) for duodenal leaks.

methodsWe performed a retrospective study of all patients who underwent EVT for duodenal perforations between 2016 and 2021 at two tertiary centers. We analyzed demographic and clinical patient characteristics, surgical outcomes, leak characteristics, sponge-related complications, and success rate.

resultsIndications for treatment with EVT in the duodenum consisted of leak after duodenal suture of a perforated ulcer (n = 4), iatrogenic perforation after endoscopic resection (n = 2), iatrogenic perforation during surgery (n = 2), and anastomotic leak after upper gastrointestinal surgery (n = 2). EVT was used as a first-line treatment in seven patients and as a second-line treatment in three patients. EVT was successfully applied in all interventions (n = 10, 100%). Overall, EVT lead to definitive closure of the defects in eight out of ten patients (80%). No severe EVT-related adverse events occurred.

conclusionEVT is safe and technically feasible, so it emerges as a promising endoscopic treatment option for duodenal leaks. However, multidisciplinary collaboration and management are important to reduce the occurrence of postoperative complications, and to improve recovery rates.

Indexed as

Duodenal UlcerNegative-Pressure Wound TherapyPeptic Ulcer PerforationAnastomotic LeakEndoscopyHumansIatrogenic DiseaseRetrospective StudiesTreatment OutcomeComplication managementDuodenal perforationEndoscopic vacuum therapyLeak managementUpper gastrointestinal surgery

Identifiers

PMID36241747
PMCPMC9568927
OpenAlexW4306249371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.