Evidence map›Paper›PMID 36241675›Full record

ArticleScientific reports2022

Methods and reference data for middle ear transfer functions.

M Koch, T M Eßinger, H Maier, J H Sim, L Ren, N T Greene, T Zahnert, M Neudert, M Bornitz

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Investigation of the coupling quality of partial prostheses at the stapes head.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

M Koch *Faculty of Medicine Carl Gustav Carus, ERCD-Ear Research Center Dresden at the Department of Otorhinolaryngology Head and Neck Surgery, TU Dresden, Fetscherstraße 74, 01307, Dresden, Germany. martin.koch@uniklinikum-dresden.de.
T M Eßinger *Faculty of Medicine Carl Gustav Carus, ERCD-Ear Research Center Dresden at the Department of Otorhinolaryngology Head and Neck Surgery, TU Dresden, Fetscherstraße 74, 01307, Dresden, Germany. tillmoritz.essinger@uniklinikum-dresden.de.
H MaierDepartment of Otolaryngology, Hannover Medical School, Carl-Neuberg-Str. 1a, 30625, Hannover, Germany.
J H SimDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
L RenEye and ENT Hospital of Fudan University, Fenyang Road 83, Shanghai, 200031, China.
N T GreeneDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Aurora, CO, USA.
T ZahnertFaculty of Medicine Carl Gustav Carus, ERCD-Ear Research Center Dresden at the Department of Otorhinolaryngology Head and Neck Surgery, TU Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
M NeudertFaculty of Medicine Carl Gustav Carus, ERCD-Ear Research Center Dresden at the Department of Otorhinolaryngology Head and Neck Surgery, TU Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
M BornitzFaculty of Medicine Carl Gustav Carus, ERCD-Ear Research Center Dresden at the Department of Otorhinolaryngology Head and Neck Surgery, TU Dresden, Fetscherstraße 74, 01307, Dresden, Germany.

Funding

Improving an animal model of human hearing loss: quantifying risks associated with common otolaryngology proceduresR21DC017809 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI GREENE, NATHANIEL TUSSING · 2019 to 2021
$467k
NIDCD NIH HHS R21 DC017809
6 · The paper itself

Abstract

Human temporal bone specimens are used in experiments measuring the sound transfer of the middle ear, which is the standard method used in the development of active and passive middle ear implants. Statistical analyses of these experiments usually require that the TB samples are representative of the population of non-pathological middle ears. Specifically, this means that the specimens must be mechanically well-characterized. We present an in-depth statistical analysis of 478 data sets of middle ear transfer functions (METFs) from different laboratories. The data sets are preprocessed and various contributions to the variance of the data are evaluated. We then derive a statistical range as a reference against which individual METF measurements may be validated. The range is calculated as the two-sided 95% tolerance interval at audiological frequencies. In addition, the mean and 95% confidence interval of the mean are given as references for assessing the validity of a sample group. Finally, we provide a suggested procedure for measuring METFs using the methods described herein.

Indexed as

Ossicular ProsthesisEar, MiddleHumansSoundTemporal Bone

Identifiers

PMID36241675
PMCPMC9568555

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.