Evidence map›Paper›PMID 36241423›Full record

ArticleJournal of neurology, neurosurgery, and psychiatry2023

Quantitative epileptiform burden and electroencephalography background features predict post-traumatic epilepsy.

Yilun Chen, Songlu Li, Wendong Ge, Jin Jing, Hsin Yi Chen, Daniel Doherty, Alison Herman, Safa Kaleem, Kan Ding, Gamaleldin Osman and 16 more

Open access · greenAbstract read
In one paragraph

Article in Journal of neurology, neurosurgery, and psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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  10. Computational Prognostic Modeling in Traumatic Brain Injury.Advances in experimental medicine and biology · 2024
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 10 institutions in 1 country.

Yilun ChenNeurology, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-2348-7531
Songlu LiNeurology, Yale School of Medicine, New Haven, Connecticut, USA.
Wendong GeNeurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jin JingNeurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Hsin Yi ChenNeurology, Yale School of Medicine, New Haven, Connecticut, USA.
Daniel DohertyNeurology, Yale School of Medicine, New Haven, Connecticut, USA.
Alison HermanNeurology, Yale School of Medicine, New Haven, Connecticut, USA.
Safa KaleemNeurology, Duke University School of Medicine, Durham, North Carolina, USA.
Kan DingNeurology, UT Southwestern Medical Center, Dallas, Texas, USA.
Gamaleldin OsmanNeurology, Henry Ford Health System, Detroit, Michigan, USA.
Christa B SwisherNeurology, Duke University School of Medicine, Durham, North Carolina, USA.
Christine SmithNeurology, University of Florida College of Medicine, Gainesville, Florida, USA.
Carolina B MacielNeurology, Yale School of Medicine, New Haven, Connecticut, USA.
Ayham AlkhachroumNeurology, University of Miami Miller School of Medicine, Miami, Florida, USA.ORCID 0000-0003-0352-5913
Jong Woo LeeNeurology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Monica B DhakarNeurology, Emory University School of Medicine, Atlanta, Georgia, USA.
Emily J GilmoreNeurology, Yale School of Medicine, New Haven, Connecticut, USA.
Adithya SivarajuNeurology, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-6027-9205
Lawrence J HirschNeurology, Yale School of Medicine, New Haven, Connecticut, USA.
Sacit B OmayNeurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Hal BlumenfeldNeurology, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0003-0812-8132
Kevin N ShethNeurology, Yale School of Medicine, New Haven, Connecticut, USA.
Aaron F StruckNeurology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.
Brian L EdlowNeurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
M Brandon WestoverNeurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jennifer A KimNeurology, Yale School of Medicine, New Haven, Connecticut, USA jennifer.a.kim@yale.edu.ORCID 0000-0003-3072-6198
Yale University · USMassachusetts General Hospital · USDuke University · USBrigham and Women's Hospital · USEmory University · USHenry Ford Health System · USSouthwestern Medical CenterUniversity of Florida · USUniversity of Miami · USUniversity of Wisconsin–Madison · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Miami Clinical and Translational Science InstituteUL1TR002736 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, KOBETZ, ERIN N · 2018 to 2022
$23.2M
UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
Neuroscience Resident Research ProgramR25NS065743 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CASH, SYDNEY S, WILLIAMS, ZIV · 2009 to 2023
$11.8M
The Late Effects of TBI (LETBI) Study: Injury Patterns and Biological Markers of Post-Traumatic NeurodegenerationRF1NS115268 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Kristen Dams-O'Connor · 2019 to 2026
$10.3M
Data-Driven Sleep Biomarkers of Brain Health, Heart Health, and MortalityR01HL161253 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI CLIFFORD, GARI DAVID, MIGNOT, EMMANUEL J · 2022 to 2025
$8.3M
Comparative Safety of Seizure Prophylaxis within the Medicare ProgramR01AG073410 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Lidia Maria Veras Rocha de Moura · 2021 to 2026
$4.1M
Integrative Motor Activity Biomarker for the Risk of Alzheimer's RiskRF1AG064312 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, KUN · 2019 to 2019
$3.6M
Multimodal Network Connectivity Architecture (MOCA) of the Brain and its Role in the Recovery of Consciousness in Comatose Cardiac Arrest PatientsR01NS102574 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI GREER, DAVID MATTHEW, WU, ONA · 2018 to 2022
$3.4M
ELECTRO-BOOST: Electroencephalography for cerebral trauma recovery and oxygenationR01NS117904 · NINDS · YALE UNIVERSITY · PI DING, KAN, GILMORE, EMILY · 2020 to 2025
$3.2M
Investigation of Sleep in the Intensive Care Unit (ICU-SLEEP)R01NS102190 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI WESTOVER, MICHAEL BRANDON · 2018 to 2022
$3.2M
NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR001427NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR002736NHLBI NIH HHS R01 HL161253NIA NIH HHS R01 AG073410NIA NIH HHS R34 AG061304NIA NIH HHS RF1 AG064312NICHD NIH HHS DP2 HD101400NINDS NIH HHS F30 NS060325NINDS NIH HHS K23 NS110980NINDS NIH HHS K23 NS112596NINDS NIH HHS R01 NS102190NINDS NIH HHS R01 NS102574NINDS NIH HHS R01 NS107291NINDS NIH HHS R01 NS111022NINDS NIH HHS R01 NS117904NINDS NIH HHS R01 NS126282NINDS NIH HHS R21 NS109627NINDS NIH HHS R21 NS128641NINDS NIH HHS R25 NS065743NINDS NIH HHS RF1 NS115268NINDS NIH HHS RF1 NS120947
6 · The paper itself

Abstract

backgroundPost-traumatic epilepsy (PTE) is a severe complication of traumatic brain injury (TBI). Electroencephalography aids early post-traumatic seizure diagnosis, but its optimal utility for PTE prediction remains unknown. We aim to evaluate the contribution of quantitative electroencephalograms to predict first-year PTE (PTE

methodsWe performed a multicentre, retrospective case-control study of patients with TBI. 63 PTE

resultsIn the matched cohort (n=126), greater epileptiform burden, suppression burden and beta variability were associated with 4.6 times higher PTE

conclusionsEpileptiform and spectral characteristics enhance covariates identified on TBI admission and CT abnormalities in PTE

Indexed as

Brain Injuries, TraumaticEpilepsy, Post-TraumaticCase-Control StudiesElectroencephalographyHumansRetrospective StudiesEEGEPILEPSYTRAUMATIC BRAIN INJURY

Identifiers

PMID36241423
PMCPMC9931627
OpenAlexW4306181180

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.