Research on multi-modal autonomous diagnosis algorithm of COVID-19 based on whale optimized support vector machine and improved D-S evidence fusion.

Aiming at the problem that the single CT image signal feature recognition method in the self-diagnosis of diseases cannot accurately and reliably classify COVID-19, and it is easily confused with suspected cases. The collected CT signals and experimental indexes are extracted to construct different feature vectors. The support vector machine is optimized by the improved whale algorithm for the preliminary diagnosis of COVID-19, and the basic probability distribution function of each evidence is calculated by the posterior probability modeling method. Then the similarity measure is introduced to optimize the basic probability distribution function. Finally, the multi-domain feature fusion prediction model is established by using the weighted D-S evidence theory. The experimental results show that the fusion of multi-domain feature information by whale optimized support vector machine and improved D-S evidence theory can effectively improve the accuracy and the precision of COVID-19 autonomous diagnosis. The method of replacing a single feature parameter with multi-modal indicators (CT, routine laboratory indexes, serum cytokines and chemokines) provides a more reliable signal source for the diagnosis model, which can effectively distinguish COVID-19 from the suspected cases.