Evidence map›Paper›PMID 36240286›Full record

ArticleScience immunology2022

Resident T

Agnieszka M Kabat, Alexandra Hackl, David E Sanin, Patrice Zeis, Katarzyna M Grzes, Francesc Baixauli, Ryan Kyle, George Caputa, Joy Edwards-Hicks, Matteo Villa and 11 more

Abstract read
In one paragraph

Article in Science immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Involvement of increased arginase-1The Journal of international medical research · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. The immunology of sickness metabolism.Cellular & molecular immunology · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 3 countries.

Agnieszka M KabatMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0003-1916-5983
Alexandra HacklMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.
David E SaninMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0003-0188-7267
Patrice ZeisMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0001-7615-2201
Katarzyna M GrzesMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0002-5158-1111
Francesc BaixauliMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0002-9676-2901
Ryan KyleMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0002-8146-7504
George CaputaMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.
Joy Edwards-HicksMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0002-9313-5718
Matteo VillaMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0003-2684-0596
Nisha RanaMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.
Jonathan D CurtisMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0001-6048-878X
Angela CastoldiMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0002-8434-7989
Jovana CupovicMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.
Leentje DreesenDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-5578-1877
Maria SibiliaInstitute of Cancer Research, Medical University of Vienna, Comprehensive Cancer Center, Borschkegasse 8a, Vienna A-1090, Austria.ORCID 0000-0001-6129-5613
J Andrew PospisilikCenter for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA.ORCID 0000-0002-9745-0977
Joseph F UrbanUSDA, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics, and Immunology Laboratory, and Belstville Agricultural Research Service, Animal Parasitic Disease Laboratory, Beltsville, MD 20705, USA.ORCID 0000-0002-1590-8869
Dominic GrünMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.
Erika L PearceMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0001-5592-5439
Edward J PearceMax Planck Institute for Immunobiology and Epigenetics, Freiburg 79108, Germany.ORCID 0000-0003-1001-9656
Max Planck Institute of Immunobiology and Epigenetics · DEBloomberg (United States) · USUniversity of Freiburg · DEBeltsville Human Nutrition Research Center · USComprehensive Cancer Center Vienna · ATVan Andel Institute · USWashington University in St. Louis · US

Funding

MACROPHAGE FATTY ACID METABOLISM IN IMMUNITY TO HELMINTHSR01AI110481 · NIAID · WASHINGTON UNIVERSITY · PI PEARCE, EDWARD J. · 2015 to 2019
$1.5M
NIAID NIH HHS R01 AI110481
6 · The paper itself

Abstract

Type 2 immunity is associated with adipose tissue (AT) homeostasis and infection with parasitic helminths, but whether AT participates in immunity to these parasites is unknown. We found that the fat content of mesenteric AT (mAT) declined in mice during infection with a gut-restricted helminth. This was associated with the accumulation of metabolically activated, interleukin-33 (IL-33), thymic stromal lymphopoietin (TSLP), and extracellular matrix (ECM)-producing stromal cells. These cells shared transcriptional features, including the expression of

Indexed as

Immunity, InnateInterleukin-33Adipose TissueAmphiregulinAnimalsCytokinesDipeptidyl Peptidase 4ErbB ReceptorsLymphocytesMiceTh2 CellsTransforming Growth Factor beta1AmphiregulinCytokinesDipeptidyl Peptidase 4ErbB ReceptorsInterleukin-33Transforming Growth Factor beta1

Identifiers

PMID36240286
PMCPMC11905186
OpenAlexW4306182256

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.