Evidence map›Paper›PMID 36240262›Full record

ArticlePloS one2022

Prevalence of hepatitis B virus and immunity status among healthcare workers in Beira City, Mozambique.

Nédio Mabunda, Lúcia Vieira, Imelda Chelene, Cremildo Maueia, Ana Flora Zicai, Ana Duajá, Falume Chale, Lúcia Chambal, Adolfo Vubil, Orvalho Augusto

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  6. Immune response to GeneVac-BIJID regions · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Nédio MabundaInstituto Nacional de Saúde, Marracuene, Mozambique.ORCID 0000-0002-1848-4627
Lúcia VieiraInstituto Nacional de Saúde, Delegação Provincial de Sofala, Beira, Mozambique.
Imelda CheleneInstituto Nacional de Saúde, Marracuene, Mozambique.
Cremildo MaueiaInstituto Nacional de Saúde, Marracuene, Mozambique.
Ana Flora ZicaiInstituto Nacional de Saúde, Marracuene, Mozambique.
Ana DuajáInstituto Nacional de Saúde, Delegação Provincial de Sofala, Beira, Mozambique.
Falume ChaleInstituto Nacional de Saúde, Delegação Provincial de Sofala, Beira, Mozambique.
Lúcia ChambalFaculty of Medicine, Universidade Eduardo Mondlane, Maputo, Mozambique.
Adolfo VubilInstituto Nacional de Saúde, Marracuene, Mozambique.
Orvalho AugustoFaculty of Medicine, Universidade Eduardo Mondlane, Maputo, Mozambique.ORCID 0000-0002-0005-3968
Instituto Nacional de Saúde · MZEduardo Mondlane University · MZCatholic University of Mozambique · MZUniversity of Cape Town · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatitis B virus (HBV) infection can be prevented by vaccination. Exposure to blood or body fluids poses a high risk of transmission of HBV in health care workers (HCWs). This study aimed to determine the prevalence of markers of exposure, susceptibility, and protection to HBV infection in HCWs in Beira, Mozambique.

methodsA cross-sectional study was conducted between June and August 2020 in Beira City, Mozambique, in HCWs based on self-administered questionnaires and blood samples. Plasma samples were tested for HBV surface antigen (HBsAg), antibodies to HBV core antigen (anti-HBc), antibodies to HBsAg (anti-HBs) and HBV viral load (HBV DNA).

resultsMost of the 315 HCWs in the study were nurses (125; 39.7%). Of the HCWs, 5.1% (16; 95% Confidence Interval (CI): 2.9 to 8.1%) were infected by HBV (HBsAg and/or HBV DNA positive). Occult HBV infection (OBI) (HBV DNA positive and HBsAg negative) was found in 0.3% (1; 95% CI: 0.0 to 1.8%) of participants; 27.9% (88; 95% CI: 23.1 to 33.2%) were susceptible (negative for all markers), 6.3% (20; 95% CI: 3.9 to 9.6) were immune due to natural infection (anti-HBs and anti-HBc positive only), while 60% (189; 95% CI: 54.4 to 65.5) were immune due to vaccination (anti-HBs positive only).

conclusionThis study showed a high intermediate prevalence of chronic hepatitis B among healthcare workers in Beira City, Central Mozambique, and one-third of healthcare workers were susceptible to HBV infection. There is a need to implement a national hepatitis B screening and vaccination strategy among healthcare workers in Mozambique.

Indexed as

Hepatitis BHepatitis B, ChronicAntigens, SurfaceCross-Sectional StudiesDNA, ViralHealth PersonnelHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B virusHumansMozambiquePrevalenceAntigens, SurfaceDNA, ViralHepatitis B AntibodiesHepatitis B Surface Antigens

Identifiers

PMID36240262
PMCPMC9565706
OpenAlexW4306247792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.