Evidence map›Paper›PMID 36240220›Full record

ArticlePloS one2022

Adherence to multidisciplinary care in a prospective chronic kidney disease cohort is associated with better outcomes.

Pablo Rios, Laura Sola, Alejandro Ferreiro, Ricardo Silvariño, Verónica Lamadrid, Laura Ceretta, Liliana Gadola, all nephrologists who report to Programa de Salud Renal Uruguay Registry

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Mind the gap in kidney care: Translating what we know into what we do.Journal of family medicine and primary care · 2024
    Article
  11. Article
  12. Article
  13. Mind the Gap in Kidney Care: Translating What We Know Into What We do.Canadian journal of kidney health and disease · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pablo RiosComisión Asesora de Programa de Salud Renal, Fondo Nacional de Recursos, Montevideo, Uruguay.ORCID 0000-0002-0778-822X
Laura SolaComisión Asesora de Programa de Salud Renal, Fondo Nacional de Recursos, Montevideo, Uruguay.
Alejandro FerreiroComisión Asesora de Programa de Salud Renal, Fondo Nacional de Recursos, Montevideo, Uruguay.ORCID 0000-0001-6819-8058
Ricardo SilvariñoComisión Asesora de Programa de Salud Renal, Fondo Nacional de Recursos, Montevideo, Uruguay.ORCID 0000-0002-0416-2694
Verónica LamadridComisión Asesora de Programa de Salud Renal, Fondo Nacional de Recursos, Montevideo, Uruguay.
Laura CerettaComisión Asesora de Programa de Salud Renal, Fondo Nacional de Recursos, Montevideo, Uruguay.
Liliana GadolaComisión Asesora de Programa de Salud Renal, Fondo Nacional de Recursos, Montevideo, Uruguay.ORCID 0000-0001-5041-4760
all nephrologists who report to Programa de Salud Renal Uruguay Registry

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Renal Healthcare Program Uruguay (NRHP-UY) is a national, multidisciplinary program that provides care to chronic kidney disease (CKD) patients. In this study, we report the global results of CKD patient outcomes and a comparison between those treated at the NRHP-UY Units, with those patients who were initially included in the program but did not adhere to follow up.

methodsA cohort of not-on dialysis CKD patients included prospectively in the NRHP-UY between October 1st 2004 and September 30th 2017 was followed-up until September 30th 2019. Two groups were compared: a) Nephrocare Group: Patients who had at least one clinic visit during the first year on NRHP-UY (n = 11174) and b) Non-adherent Group: Patients who were informed and accepted to be included but had no subsequent data registered after admission (n = 3485). The study was approved by the Ethics Committee and all patients signed an informed consent. Outcomes were studied with Logistic and Cox´s regression analysis, Fine and Gray competitive risk and propensity-score matching tests.

results14659 patients were analyzed, median age 70 (60-77) years, 56.9% male. The Nephrocare Group showed improved achievement of therapeutic goals, ESKD was more frequent (HR 2.081, CI 95%1.722-2.514) as planned kidney replacement therapy (KRT) start (OR 2.494, CI95% 1.591-3.910), but mortality and the combined event (death and ESKD) were less frequent (HR 0.671, CI95% 0.628-0.717 and 0.777, CI95% 0.731-0.827) (p = 0.000) compared to the Non-adherent group. Results were similar in the propensity-matched group: ESKD (HR 2.041, CI95% 1.643-2.534); planned kidney replacement therapy (KRT) start (OR 2.191, CI95% 1.322-3.631) death (HR 0.692, CI95% 0.637-0.753); combined event (HR 0.801, CI95% 0.742-0.865) (p = 0.000).

conclusionMultidisciplinary care within the NRHP-UY is associated with timely initiation of KRT and lower mortality in single outcomes, combined analysis, and propensity-matched analysis.

Indexed as

Kidney Failure, ChronicRenal Insufficiency, ChronicAgedCohort StudiesDisease ProgressionFemaleHumansMaleProspective StudiesRenal Replacement Therapy

Identifiers

PMID36240220
PMCPMC9565398

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.