Evidence map›Paper›PMID 36240190›Full record

ArticlePloS one2022

Noninvasive evaluation of the hemodynamic status in patients after heart transplantation or left ventricular assist device implantation.

Sebastian Roth, Henrik Fox, René M'Pembele, Michiel Morshuis, Giovanna Lurati Buse, Markus W Hollmann, Ragnar Huhn, Thomas Bitter

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Sebastian RothDepartment of Anesthesiology, University Hospital Duesseldorf, Duesseldorf, Germany.
Henrik FoxClinic for Thoracic and Cardiovascular Surgery, Herz- und Diabeteszentrum NRW, Ruhr Universität Bochum, Bad Oeynhausen, Germany.ORCID 0000-0002-2187-8715
René M'PembeleDepartment of Anesthesiology, University Hospital Duesseldorf, Duesseldorf, Germany.
Michiel MorshuisClinic for Thoracic and Cardiovascular Surgery, Herz- und Diabeteszentrum NRW, Ruhr Universität Bochum, Bad Oeynhausen, Germany.
Giovanna Lurati BuseDepartment of Anesthesiology, University Hospital Duesseldorf, Duesseldorf, Germany.
Markus W HollmannDepartment of Anesthesiology, Amsterdam University Medical Center (AUMC), Amsterdam, The Netherlands.ORCID 0000-0001-8248-0244
Ragnar HuhnDepartment of Anesthesiology, University Hospital Duesseldorf, Duesseldorf, Germany.ORCID 0000-0002-3114-7190
Thomas BitterDepartment of Pneumology and Respiratory Medicine, Staedtisches Klinikum Braunschweig, Braunschweig, Germany.
Düsseldorf University Hospital · DEHeart and Diabetes Center North Rhine-Westphalia · DEAmsterdam University Medical Centers · NLKlinikum Braunschweig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHemodynamic assessment is crucial after heart transplantation (HTX) or left ventricular assist device (LVAD) implantation. Gold-standard is invasive assessment via thermodilution (TD). Noninvasive pulse contour analysis (NPCA) is a new technology that is supposed to determine hemodynamics completely noninvasive. We aimed to validate this technology in HTX and LVAD patients and conducted a prospective single-center cohort study.

methodsPatients after HTX or LVAD implantation underwent right heart catheterization including TD. NPCA using the CNAP Monitor (V.5.2.14; CNSystems Medizintechnik AG, Graz, Austria) was performed simultaneously. Three TD measurements were compared with simultaneous NPCA measurements for hemodynamic assessment. To describe the agreement between TD and NPCA, Bland-Altman analysis was done.

resultsIn total, 28 patients were prospectively enrolled (HTX: n = 10, LVAD: n = 18). Bland-Altman analysis revealed a mean bias of +1.05 l/min (limits of agreement ± 4.09 l/min, percentage error 62.1%) for cardiac output (CO). In LVAD patients, no adequate NPCA signal could be obtained. In 5 patients (27.8%), any NPCA signal could be detected, but was considered as low signal quality.

conclusionIn conclusion, according to our limited data in a small cohort of HTX and LVAD patients, NPCA using the CNAP Monitor seems not to be suitable for noninvasive evaluation of the hemodynamic status.

Indexed as

Heart-Assist DevicesHeart FailureHeart TransplantationCohort StudiesHemodynamicsHumansProspective Studies

Identifiers

PMID36240190
PMCPMC9565384
OpenAlexW4306247831

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.