Evidence map›Paper›PMID 36239906›Full record

ArticleDermatology and therapy2022

Clinical Efficacy of a Digital Intervention for Patients with Atopic Dermatitis: a Prospective Single-Center Study.

Sigrídur Lára Gudmundsdóttir, Tommaso Ballarini, María L Ámundadóttir, Judit Mészáros, Jenna H Eysteinsdóttir, Ragna H Thorleifsdóttir, Sigrídur K Hrafnkelsdóttir, Heida B Bragadóttir, Saemundur Oddsson, Jonathan I Silverberg

Open access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  7. Knowledge assessment tools in atopic dermatitis patient education: a scoping review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Sigrídur Lára GudmundsdóttirSidekick Health, Kópavogur, Iceland.
Tommaso BallariniSidekick Health, Berlin, Germany.ORCID http://orcid.org/0000-0001-7299-5973
María L ÁmundadóttirSidekick Health, Kópavogur, Iceland.
Judit MészárosSidekick Health, Berlin, Germany. judit@sidekickhealth.com.ORCID http://orcid.org/0000-0002-8196-9061
Jenna H EysteinsdóttirHudlaeknastodin Dermatology Clinic, Kópavogur, Iceland.
Ragna H ThorleifsdóttirHudlaeknastodin Dermatology Clinic, Kópavogur, Iceland.
Sigrídur K HrafnkelsdóttirSidekick Health, Kópavogur, Iceland.
Heida B BragadóttirSidekick Health, Kópavogur, Iceland.
Saemundur OddssonSidekick Health, Kópavogur, Iceland.
Jonathan I SilverbergSchool of Medicine and Health Sciences, George Washington University, Washington, DC, USA.
Icelandic Heart Association · ISUniversity of Iceland · ISGeorge Washington University · USSick (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionImproving disease awareness and treatment adherence is key for the long-term management of atopic dermatitis (AD). Digital interventions can support patients in disease self-management and adopting a healthier lifestyle through behavioral modifications. We aimed to test the clinical efficacy of a digital program in patients with AD.

methodsAdults with mild-to-severe AD were recruited for a 6-week feasibility study. The intervention was delivered through a mobile app and consisted of symptom and trigger education, treatment reminders, lifestyle coaching, and healthy lifestyle support. Here we report the secondary outcomes of intervention efficacy on clinical symptoms, as assessed by Scoring Atopic Dermatitis (SCORAD) and Patient-Oriented Eczema Measure (POEM), on health-related quality of life (HR QoL) as assessed by Dermatology Life Quality Index (DLQI), and changes in behaviors related to disease management as assessed by a six-item questionnaire.

resultsTwenty of 21 patients (95.2%) completed the program (81% female, mean age 31.4 years, mean time from diagnosis 26.8 years). Clinical symptoms and patient-reported global severity improved by 44% and 46%, respectively, while HR QoL improved by 41% (p < 0.001 for all measures). Adherence to treatments and preventive measures improved from pre- to post-intervention, including skincare, avoidance of triggers, and disease-related knowledge. A significant interaction was observed between increased treatment adherence and clinical improvement, such that larger clinical improvements were observed in patients with higher treatment adherence.

conclusionPatients with AD are open to and can benefit from a digitally delivered targeted intervention, as demonstrated by significant improvements in treatment adherence and related clinical outcomes.

Indexed as

Atopic dermatitisDigital interventionEczemaeHealthHealth-related quality of life

Identifiers

PMID36239906
PMCPMC9588147
OpenAlexW4306166032

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.