Evidence map›Paper›PMID 36239903›Full record

ArticleSports medicine (Auckland, N.Z.)2023

Sensitivity and Specificity of the ImPACT Neurocognitive Test in Collegiate Athletes and US Military Service Academy Cadets with ADHD and/or LD: Findings from the NCAA-DoD CARE Consortium.

Lauren L Czerniak, Spencer W Liebel, Hannah Zhou, Gian-Gabriel P Garcia, Mariel S Lavieri, Michael A McCrea, Thomas W McAllister, Paul F Pasquina, Steven P Broglio, CARE Consortium Investigators

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Article in Sports medicine (Auckland, N.Z.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Lauren L CzerniakDepartment of Industrial and Operations Engineering, University of Michigan, Ann Arbor, MI, USA. czernL@umich.edu.ORCID http://orcid.org/0000-0003-4379-2004
Spencer W LiebelDepartment of Neurology, University of Utah, Salt Lake City, UT, USA.
Hannah ZhouDepartment of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, USA.
Gian-Gabriel P GarciaH. Milton Stewart School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Mariel S LavieriDepartment of Industrial and Operations Engineering, University of Michigan, Ann Arbor, MI, USA.
Michael A McCreaDepartments of Neurosurgery and Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
Thomas W McAllisterDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Paul F PasquinaDepartment of Physical Medicine and Rehabilitation, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Steven P BroglioMichigan Concussion Center, University of Michigan, Ann Arbor, MI, USA.
CARE Consortium Investigators
University of Michigan · USIndiana University School of MedicineGeorgia Institute of Technology · USMedical College of Wisconsin · USUniformed Services University of the Health Sciences · USUniversity of Utah · US

Funding

National Science Foundation (United States) 1841052U.S. Department of Defense W81XWH1820047
6 · The paper itself

Abstract

BACKGROUND AND

objectiveComputer-based neurocognitive tests are widely used in sport-related concussion management, but the performance of these tests is not well understood in the participant population with attention-deficit/hyperactivity disorder (ADHD) and/or learning disorder (LD). This research estimates the sensitivity and specificity performance of the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) computer-based neurocognitive test in identifying concussion in this population.

methodsStudy participants consisted of collegiate university athletes and military service academy cadets from the National Collegiate Athletic Association-Department of Defense CARE Consortium who completed the ImPACT test between 2014 and 2021. Participants who self-identified as belonging to one of the subgroups of interest (ADHD with or without LD [ADHD:LD+/-], LD with or without ADHD [LD:ADHD+/-], ADHD and/or LD [ADHD a/o LD]) and completed a baseline (1874 ADHD:LD+/-, 779 LD:ADHD+/-, 2338 ADHD a/o LD) or 24-48 h post-concussion (175 ADHD:LD+/-, 77 LD:ADHD+/-, 216 ADHD a/o LD) ImPACT assessment were included. Sensitivity and specificity were calculated using a normative data method and three machine learning classification methods: logistic regression, classification and regression tree, and random forest.

resultsUsing the four methods, participants with ADHD:LD+/- had sensitivities that ranged from 0.474 to 0.697, and specificities that ranged from 0.538 to 0.686. Participants with LD:ADHD+/- had sensitivities that ranged from 0.455 to 0.688, and specificities that ranged from 0.456 to 0.588. For participants with ADHD a/o LD, sensitivities ranged from 0.542 to 0.755, and specificities ranged from 0.451 to 0.724.

conclusionsFor all subgroups and analytical methods, the results illustrate sensitivity and specificity values below typically accepted levels indicative of clinical utility. These findings support that using ImPACT alone may be insufficient to inform concussion diagnoses and encourages the use of a multi-dimensional concussion assessment.

Indexed as

Athletic InjuriesAttention Deficit Disorder with HyperactivityBrain ConcussionLearning DisabilitiesMilitary PersonnelAthletesHumansMental Status and Dementia TestsNeuropsychological Tests

Identifiers

PMID36239903
OpenAlexW4306168629

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.