Evidence map›Paper›PMID 36239837›Full record

ArticleInternational ophthalmology2023

Influence of video display terminal use and meibomian gland dysfunction on the ocular surface and tear neuromediators.

Ahmet Alp Bilgic, Sibel Kocabeyoglu, Ozlem Dikmetas, Cagman Tan, Jale Karakaya, Murat Irkec

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In one paragraph

Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ahmet Alp BilgicDepartment of Ophthalmology, Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey. ahmetalp55@gmail.com.ORCID http://orcid.org/0000-0001-8033-7970
Sibel KocabeyogluDepartment of Ophthalmology, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-6595-3687
Ozlem DikmetasDepartment of Ophthalmology, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-5670-2384
Cagman TanDepartment of Pediatric Immunology, Institute of Child Health, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-6972-1349
Jale KarakayaDepartment of Biostatistics, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-7222-7875
Murat IrkecDepartment of Ophthalmology, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-8892-4811
Hacettepe University · TRDışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effects of video display terminal (VDT) work and meibomian gland dysfunction (MGD) on ocular surface parameters, tear cytokine and substance P (SP) levels, and their association with dry eye disease (DED).

methodsThis cross-sectional study included 60 patients with evaporative DED and 20 healthy individuals. The DED patients were divided into three groups according to daily VDT work time and presence of MGD. The ocular surface and tear film were assessed using the Ocular Surface Disease Index questionnaire (OSDI), tear film break-up time (TBUT), ocular surface staining, Schirmer II test, and corneal sensitivity. MGD was evaluated with meibography. Corneal nerve alterations were evaluated using in vivo confocal microscopy (IVCM). The tear levels of 30 cytokines and SP were examined.

resultsCompared to controls, DED patients had higher OSDI score (p < 0.001), increased corneal staining with fluorescein and lissamine green (p = 0.046, p = 0,038), and lower TBUT (p < 0.001). Tear interleukin-6 levels were higher in DED patients, while tear SP levels did not differ between the groups (p = 0.265). VDT work time showed a weak positive correlation with OSDI (r = 0.274, p = 0.014) and SP level (r = 0.284, p = 0.011).

conclusionThe results of this study show that VDT use and MGD have an adverse effect on the ocular surface. It was also observed that the combination of VDT use and MGD did not significantly increase the ocular surface disease, but longer VDT exposure may be associated with more complaints of ocular discomfort.

Indexed as

Dry Eye SyndromesMeibomian Gland DysfunctionComputer TerminalsCorneaCross-Sectional StudiesCytokinesHumansMeibomian GlandsTearsCytokinesEvaporative dry eyeIn vivo confocal microscopyMeibomian gland dysfunctionSubstance PTear neuromediatorsVideo display terminal

Identifiers

PMID36239837
OpenAlexW4306167608

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.