Evidence map›Paper›PMID 36239830›Full record

Trial reportJournal of autism and developmental disorders2024

Stepped-Care Cognitive Behavioral Therapy in Children on the Autism Spectrum with Co-occurring Anxiety.

Eric A Storch, Sophie C Schneider, Sean M Olsen, Ana C Ramirez, Leandra N Berry, Robin P Goin-Kochel, Morgan McNeel, Abigail E Candelari, Andrew G Guzick, Sandra L Cepeda and 5 more

Abstract readClinical Trial
In one paragraph

Trial report in Journal of autism and developmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Eric A StorchDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA. eric.storch@bcm.edu.
Sophie C SchneiderDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Sean M OlsenDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Ana C RamirezDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Leandra N BerryDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Robin P Goin-KochelDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Morgan McNeelDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Abigail E CandelariDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Andrew G GuzickDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Sandra L CepedaDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
Saira WeinzimmerDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Robert G VoigtDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Troy QuastCollege of Public Health, University of South Florida, Tampa, FL, USA.
Wayne K GoodmanDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Alison SalloumSchool of Social Work, University of South Florida, Tampa, FL, USA.

Funding

Preclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MIRJANA MALETIC-SAVATIC · 2020 to 2026
$9.9M
Optimized Affective Computing Measures of Social Processes and Negative Valence in Youth PsychopathologyR01MH125958 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI HERRINGTON, JOHN DAVID, STORCH, ERIC A. · 2021 to 2025
$4.5M
NICHD NIH HHS P50 HD103555NIMH NIH HHS R01 MH125958NIMH NIH HHS R01MH125958
6 · The paper itself

Abstract

This trial examined stepped-care cognitive-behavioral treatment (CBT) among 96 autistic youth with co-occurring anxiety. Step 1 included an open trial of parent-led, therapist-guided bibliotherapy. Step 2 was family-based CBT for those who did not respond to Step 1 or maintenance for those who did. Eighteen participants (28%) who completed Step 1 responded. Responders reported significantly lower pre-treatment anxiety, internalizing symptoms, and functional impairment than non-responders. After Steps 1 and 2, 80% of completers (55% intent-to-treat) were responders. Anxiety, impairment, and ASD-related impairments significantly improved. Youth in maintenance experienced faster improvement through post-treatment, though there were no group differences at 3-month-follow-up. A stepped approach may help some individuals in Step 1, particularly those who are less anxious.

Indexed as

Autism Spectrum DisorderAutistic DisorderCognitive Behavioral TherapyAdolescentAnxietyChildHumansTreatment OutcomeAnxietyAutism spectrum disorderChildrenCognitive behavioral therapyObsessive–compulsive disorderTreatment

Identifiers

PMID36239830
PMCPMC9561323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.