ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022
Comparison of methods for the handling of metallic dental restorations before head and neck radiotherapy.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed, 1 citations in OpenAlex.
- Interdisciplinary Collaboration in Head and Neck Cancer Care: Optimizing Oral Health Management for Patients Undergoing Radiation Therapy.Current oncology (Toronto, Ont.) · 2024Review
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2 authors at 1 institution in 1 country.
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Abstract
purposeDuring head and neck radiotherapy, backscatter from metallic dental restorations (MDRs) causes oral mucositis. Currently, two MDR handling methods are used: the replacement of MDRs with provisional restorations (MDR removal) and fabrication of dental spacers before radiotherapy. We compared the effects of these two methods on the incidence of oral mucositis during head and neck radiotherapy.
methodsWe enrolled 76 patients with MDRs who underwent radiotherapy for head and neck cancer between April 2016 and March 2020. We set grade 2 oral mucositis as an outcome. After adjustment of all covariates using the propensity score (PS), we analyzed the data using a Cox proportional hazards model. In addition, subgroup analysis was performed by stratifying the data into quintiles based on the PS.
resultsFor the incidence of grade 2 oral mucositis due to head and neck radiotherapy, the hazard ratio for the MDR removal group relative to the dental spacer group was 0.344 (95% confidence interval, 0.121-0.980; P = 0.046). Subgroup analysis showed that the hazard ratio for the MDR removal group was 0.339 (95% confidence interval, 0.122-0.943; P = 0.038).
conclusionThe results suggest that MDR replacement is superior to dental spacer fabrication in reducing the incidence of oral mucositis during head and neck radiotherapy, although MDR removal carries several associated risks.
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