ArticleBrain structure & function2023
Processing of sensory, painful and vestibular stimuli in the thalamus.
Article in Brain structure & function, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Changes of cerebral functional connectivity induced by foot reflexology in a RCT.Scientific reports · 2023Trial
- Altered central vestibular processing in Parkinson's disease with Pisa syndrome.Scientific reports · 2026Article
- A motor thalamic site in humans that suppresses involuntary breathing without awareness.Journal of neurophysiology · 2026Article
- Vestibular nucleus-thalamus-cortex pathway abnormalities persist in patients with chronic unilateral vestibulopathy after the establishment of vestibular static compensation.Quantitative imaging in medicine and surgery · 2026Article
- Gray matter alterations and pain-related emotional processing in patients with adenomyosis-associated dysmenorrhea: a neuroimaging perspective.Quantitative imaging in medicine and surgery · 2025Article
- Ventral Anterior-Lateral Complex of the Thalamus Mediates Chronic Stress-Induced Pain Hypersensitivity and Underlies Electroacupuncture Analgesia.Brain and behavior · 2025Article
- Danshenol B alleviates central post-stroke pain by regulating the PIK3CG/NLRP3 signaling pathway.Journal of translational medicine · 2025Article
- The Neural Correlates of Chewing Gum-A Neuroimaging Review of Its Effects on Brain Activity.Brain sciences · 2025Review
- A study on structural imaging changes and serum neurofilament light chain (NfL) levels in individuals with white matter hyperintensities, combining imaging techniques with biomarker analysis.IBRO neuroscience reports · 2025Article
- Integrative Functions of the Hypothalamus: Linking Cognition, Emotion and Physiology for Well-being and Adaptability.Annals of neurosciences · 2025Review
- fMRI-based explanations for how meditation could modulate pain processing.Frontiers in neuroscience · 2025Article
- Functional connectivity of thalamic nuclei during sensorimotor task-based fMRI at 9.4 Tesla.Frontiers in neuroscience · 2025Article
- Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research.Neuropsychiatric disease and treatment · 2025Review
- The vestibular system in pain and embodiment: cortical overlap, modulatory potential, and therapeutic perspectives.Frontiers in neuroscience · 2025Article
- Gender differences in brain activity underlying acupuncture sensations at LR3: a task-based fMRI study.Frontiers in human neuroscience · 2025Article
- Neural basis of intensity-dependent brain activity in response to mechanical stimulation and the level of pain sensitivity.Frontiers in human neuroscience · 2025Article
- A narrative on the neurobiological roots of attachment-system functioning.Communications psychology · 2024Review
- Topography of Cholinergic Nerve Terminal Vulnerability and Balance Self-Efficacy in Parkinson's Disease.Journal of integrative neuroscience · 2024Observational
- Simultaneous cortical, subcortical, and brainstem mapping of sensory activation.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Simultaneous cortical, subcortical, and brainstem mapping of sensory activation.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe thalamus plays an important role in the mediation and integration of various stimuli (e.g., somatosensory, pain, and vestibular). Whether a stimulus-specific and topographic organization of the thalamic nuclei exists is still unknown. The aim of our study was to define a functional, in vivo map of multimodal sensory processing within the human thalamus.
methodsTwenty healthy individuals (10 women, 21-34 years old) participated. Defined sensory stimuli were applied to both hands (innocuous touch, mechanical pain, and heat pain) and the vestibular organ (galvanic stimulation) during 3 T functional MRI.
resultsBilateral thalamic activations could be detected for touch, mechanical pain, and vestibular stimulation within the left medio-dorsal and right anterior thalamus. Heat pain did not lead to thalamic activation at all. Stimuli applied to the left body side resulted in stronger activation patterns. Comparing an early with a late stimulation interval, the mentioned activation patterns were far more pronounced within the early stimulation interval.
conclusionsThe right anterior and ventral-anterior nucleus and the left medio-dorsal nucleus appear to be important for the processing of multimodal sensory information. In addition, galvanic stimulation is processed more laterally compared to mechanical pain. The observed changes in activity within the thalamic nuclei depending on the stimulation interval suggest that the stimuli are processed in a thalamic network rather than a distinct nucleus. In particular, the vestibular network within the thalamus recruits bilateral nuclei, rendering the thalamus an important integrative structure for vestibular function.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.