ArticleJournal of the International Neuropsychological Society : JINS2023
Validity of the NIH toolbox cognitive battery in a healthy oldest-old 85+ sample.
Article in Journal of the International Neuropsychological Society : JINS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Psychometric properties of the NIH Toolbox Cognition Battery composites in older adults at risk for Alzheimer's disease and related dementias: A systematic review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Pooled it
- A world view: Considerations of sociocultural diversity in the study of subjective cognitive decline in Alzheimer's disease and related dementias.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Neuroimaging Correlates of the NIH Toolbox Cognition and Trail Making Tests: Normative Benchmarks in Healthy Aging.Clinical and translational neuroscience · 2026Article
- Exploring the link between National Institutes of Health (NIH) Toolbox Cognition Battery performance and everyday functioning in mild cognitive impairment.Neuropsychology · 2026Article
- Neurodevelopment and brain maturation in late preterm children: insights from the adolescent brain cognitive development (ABCD) study.Frontiers in pediatrics · 2026Article
- Cross-domain latent profiles of MCI and dementia are most differentiated by social and emotional functioning.Journal of the International Neuropsychological Society : JINS · 2025Article
- Evaluating the factor structure and construct validity of the NIH toolbox in older adults, with a focus on cognitive normalcy and amnestic mild cognitive impairment: considerations for diversity, including insights from persons over 85 years of age and Black older Americans.Journal of the International Neuropsychological Society : JINS · 2025Article
- Measuring Multidimensional Aspects of Health in the Oldest Old Using the NIH Toolbox: Results From the ARMADA Study.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024Article
- Exploring symptom clusters in mild cognitive impairment and dementia with the NIH Toolbox.Journal of the International Neuropsychological Society : JINS · 2024Article
- Edge-Community Entropy Is a Novel Neural Correlate of Aging and Moderator of Fluid Cognition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Associations between physical exercise type, fluid intelligence, executive function, and processing speed in the oldest-old (85 +).GeroScience · 2024Article
- Association of chronotype with language and episodic memory processing in children: implications for brain structure.Frontiers in integrative neuroscience · 2024Article
- Music-based multicomponent exercise training for community-dwelling older adults with mild-to-moderate cognitive decline: a feasibility study.Frontiers in medicine · 2023Article
Corrections and comments
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Authors and funding
20 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate the construct validity of the NIH Toolbox Cognitive Battery (NIH TB-CB) in the healthy oldest-old (85+ years old).
methodOur sample from the McKnight Brain Aging Registry consists of 179 individuals, 85 to 99 years of age, screened for memory, neurological, and psychiatric disorders. Using previous research methods on a sample of 85 + y/o adults, we conducted confirmatory factor analyses on models of NIH TB-CB and same domain standard neuropsychological measures. We hypothesized the five-factor model (Reading, Vocabulary, Memory, Working Memory, and Executive/Speed) would have the best fit, consistent with younger populations. We assessed confirmatory and discriminant validity. We also evaluated demographic and computer use predictors of NIH TB-CB composite scores.
resultsFindings suggest the six-factor model (Vocabulary, Reading, Memory, Working Memory, Executive, and Speed) had a better fit than alternative models. NIH TB-CB tests had good convergent and discriminant validity, though tests in the executive functioning domain had high inter-correlations with other cognitive domains. Computer use was strongly associated with higher NIH TB-CB overall and fluid cognition composite scores.
conclusionThe NIH TB-CB is a valid assessment for the oldest-old samples, with relatively weak validity in the domain of executive functioning. Computer use's impact on composite scores could be due to the executive demands of learning to use a tablet. Strong relationships of executive function with other cognitive domains could be due to cognitive dedifferentiation. Overall, the NIH TB-CB could be useful for testing cognition in the oldest-old and the impact of aging on cognition in older populations.
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Registered trials
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