Evidence map›Paper›PMID 36239137›Full record

ArticleDiabetes, obesity & metabolism2023

Weight regain after behavioural weight management programmes and its impact on quality of life and cost effectiveness: Evidence synthesis and health economic analyses.

Jamie Hartmann-Boyce, Linda J Cobiac, Annika Theodoulou, Jason L Oke, Ailsa R Butler, Peter Scarborough, Anastasios Bastounis, Anna Dunnigan, Rimu Byadya, F D Richard Hobbs and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes, obesity & metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. [Cost-effectiveness of the Lose Weight, Gain Life program].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jamie Hartmann-BoyceRadcliffe Primary Care Building, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0001-9898-3049
Linda J CobiacSchool of Medicine and Dentistry, Griffith University, Brisbane, Queensland, Australia.
Annika TheodoulouNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Jason L OkeNIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Ailsa R ButlerNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Peter ScarboroughNIHR Oxford Biomedical Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Anastasios BastounisNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Anna DunniganOxford University Hospitals NHS Foundation Trust, Oxford, UK.
Rimu ByadyaNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
F D Richard HobbsNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Falko F SniehottaFaculty of Medical Sciences, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Ben Amies-CullNuffield Department of Population Health, University of Oxford, Oxford, UK.
Paul Aveyard *Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-1802-4217
Susan A Jebb *Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Funding

British Heart Foundation PG/17/68/33247
6 · The paper itself

Abstract

aimsWe used data from a recent systematic review to investigate weight regain after behavioural weight management programmes (BWMPs, sometimes referred to as lifestyle modification programmes) and its impact on quality-of-life and cost-effectiveness. MATERIALS AND

methodsTrial registries, databases and forward-citation searching (latest search December 2019) were used to identify randomized trials of BWMPs in adults with overweight/obesity reporting outcomes at ≥12 months, and after programme end. Two independent reviewers screened records. One reviewer extracted data and a second checked them. The differences between intervention and control groups were synthesized using mixed-effect, meta-regression and time-to-event models. We examined associations between weight difference and difference in quality-of-life. Cost-effectiveness was estimated from a health sector perspective.

resultsIn total, 155 trials (n > 150 000) contributed to analyses. The longest follow-up was 23 years post-programme. At programme end, intervention groups achieved -2.8 kg (95%CI -3.2 to -2.4) greater weight loss than controls. Weight regain after programme end was 0.12-0.32 kg/year greater in intervention relative to control groups, with a between-group difference evident for at least 5 years. Quality-of-life increased in intervention groups relative to control at programme end and thereafter returned to control as the difference in weight between groups diminished. BWMPs with this initial weight loss and subsequent regain would be cost-effective if delivered for under £560 (£8.80-£3900) per person.

conclusionsModest rates of weight regain, with persistent benefits for several years, should encourage health care practitioners and policymakers to offer obesity treatments that cost less than our suggested thresholds as a cost-effective intervention to improve long-term weight management. REGISTRATION: The review is registered on PROSPERO, CRD42018105744.

Indexed as

Quality of LifeWeight Reduction ProgramsAdultCost-Benefit AnalysisExerciseHumansObesityWeight GainWeight Losscost-effectivenessdietexercisemeta-analysisobesityquality of lifeweight management

Identifiers

PMID36239137
PMCPMC10092406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.