Evidence map›Paper›PMID 36238950›Full record

ReviewJournal of asthma and allergy2022

Research Advances in the Treatment of Allergic Rhinitis by Probiotics.

Peng Liu, Tianyong Hu, Chenglin Kang, Jiangqi Liu, Jin Zhang, Hong Ran, Xianhai Zeng, Shuqi Qiu

Open access · goldAbstract readReview
In one paragraph

Review in Journal of asthma and allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Microbiology spectrum · 2025
    Trial
  3. Trial
  4. Efficacy ofInternational archives of otorhinolaryngology · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Frontiers in microbiology · 2025
    Article
  11. Review
  12. The role ofFood science and biotechnology · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. ProbioticFrontiers in nutrition · 2023
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Peng LiuDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zunyi, People's Republic of China.
Tianyong HuDepartment of Otolaryngology, Longgang E.N.T Hospital & Shenzhen Key Laboratory of E.N.T, Institute of E.N.T Shenzhen, Shenzhen, People's Republic of China.ORCID 0000-0002-4416-6948
Chenglin KangDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zunyi, People's Republic of China.
Jiangqi LiuDepartment of Otolaryngology, Longgang E.N.T Hospital & Shenzhen Key Laboratory of E.N.T, Institute of E.N.T Shenzhen, Shenzhen, People's Republic of China.
Jin ZhangDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zunyi, People's Republic of China.
Hong RanDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zunyi, People's Republic of China.
Xianhai ZengDepartment of Otolaryngology, Longgang E.N.T Hospital & Shenzhen Key Laboratory of E.N.T, Institute of E.N.T Shenzhen, Shenzhen, People's Republic of China.
Shuqi QiuDepartment of Otolaryngology, Longgang E.N.T Hospital & Shenzhen Key Laboratory of E.N.T, Institute of E.N.T Shenzhen, Shenzhen, People's Republic of China.
Longgang Central Hospital · CNZunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic rhinitis (AR) impairs the quality of life of patients and reduces the efficiency of social work, it is an increasingly serious public medical and economic problem in the world. Conventional anti-allergic drugs for the treatment of allergic rhinitis (AR) can cause certain side effects, which limit the quality of life of patients. Therefore, it makes sense to look for other forms of treatment. Several studies in recent years have shown that probiotics have shown anti-allergic effects in various mouse and human studies. For example, the application of certain probiotic strains can effectively relieve the typical nasal and ocular symptoms of allergic rhinitis in children and adults, thereby improving the quality of life and work efficiency. At the same time, previous studies in humans and mice have found that probiotics can produce multiple effects, such as reduction of Th2 cell inflammatory factors and/or increase of Th1 cell inflammatory factors, changes in allergy-related immunoglobulins and cell migration, regulate Th1/Th2 balance or restore intestinal microbiota disturbance. For patients with limited activity or allergic rhinitis with more attacks and longer attack duration, oral probiotics have positive effects. The efficacy of probiotics in the prevention and treatment of allergic rhinitis is remarkable, but its specific mechanism needs further study. This review summarizes the research progress of probiotics in the treatment of allergic rhinitis in recent years.

Indexed as

allergy rhinitisimmune tolerancemucosal barrierprobioticsTh1/Th2 balanceTreg/Th17 balance

Identifiers

PMID36238950
PMCPMC9552798
OpenAlexW4302759477

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.