Evidence map›Paper›PMID 36238867›Full record

ArticleChemicke zvesti2018

Efficient Synthesis of Aurone Mannich Bases and Evaluation of their Antineoplastic Activity in PC-3 Prostate Cancer Cells.

Antonina V Popova, Mykhaylo S Frasinyuk, Svitlana P Bondarenko, Wen Zhang, Yanqi Xie, Zachary M Martin, Xianfeng Cai, Michael V Fiandalo, James L Mohler, Chunming Liu and 2 more

Open access · greenAbstract read
In one paragraph

Article in Chemicke zvesti, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Antonina V PopovaInstitute of Bioorganic and Petrochemistry, National Academy of Science of Ukraine, Kyiv 02094, Ukraine.
Mykhaylo S FrasinyukInstitute of Bioorganic and Petrochemistry, National Academy of Science of Ukraine, Kyiv 02094, Ukraine.
Svitlana P BondarenkoNational University of Food Technologies, Kyiv 01601, Ukraine.
Wen ZhangDepartment of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, Lexington, KY 40536-0509, USA.
Yanqi XieDepartment of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, Lexington, KY 40536-0509, USA.
Zachary M MartinDepartment of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, Lexington, KY 40536-0509, USA.
Xianfeng CaiDepartment of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, Lexington, KY 40536-0509, USA.
Michael V FiandaloDepartment of Urology, Elm & Carlton Streets, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14263, USA.
James L MohlerDepartment of Urology, Elm & Carlton Streets, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14263, USA.
Chunming LiuDepartment of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, Lexington, KY 40536-0509, USA.
David S WattDepartment of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, Lexington, KY 40536-0509, USA.
Vitaliy M SviripaCenter for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky, Lexington, KY 40536-0509, USA.
University of Kentucky · USInstitute of Bioorganic Chemistry and Petrochemistry V.P. Kukhar · UAMarkey Cancer Center · USRoswell Park Comprehensive Cancer Center · USNational University of Food Technologies · UA

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARK G FRATTINI · 1985 to 2026
$116.6M
Protein CoreP30GM110787 · NIGMS · UNIVERSITY OF KENTUCKY · PI MENDENHALL, MICHAEL D. · 2014 to 2018
$5.7M
Novel resveratrol analogs and colorectal cancer treatmentR01CA172379 · NCI · UNIVERSITY OF KENTUCKY · PI LIU, CHUNMING · 2013 to 2017
$1.5M
A Small-Molecule Inhibitor of the Terminal Steps for Intracrine Androgen Synthesis in Advanced Prostate CancerR21CA205108 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MOHLER, JAMES L · 2016 to 2017
$422k
NCI NIH HHS P30 CA016056NCI NIH HHS R01 CA172379NCI NIH HHS R21 CA205108NIGMS NIH HHS P30 GM110787
6 · The paper itself

Abstract

An efficient method for regioselective synthesis of C-7 Mannich bases of 6-hydroxyaurones was accomplished by the

Indexed as

6-hydroxyаuronesaminomеthylationMannich baseprostate cancer

Identifiers

PMID36238867
PMCPMC9555813
OpenAlexW2801780185

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.