ArticleSSM - population health2022
Childhood adversity and cardiometabolic biomarkers in mid-adulthood in the 1958 British birth cohort.
Article in SSM - population health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 19 citations in OpenAlex.
- Associations between childhood maltreatment and mid-life health risks and risky health behaviors in a nationally representative sample.SSM. Mental health · 2026Article
- Early-life determinants of cardiometabolic outcomes and accelerated biological ageing in Colombia.Aging · 2026Article
- Plasma Multiomics Links Early-Life Adversity to Disease and Cardiometabolic Health: A Population-Based Cohort Study.Journal of the American Heart Association · 2026Article
- Associations between adverse childhood experiences and cardiometabolic health in later adulthood in Colombia.Journal of epidemiology and community health · 2026Article
- Association of pre-adolescent adverse childhood experiences with adolescent cholesterol levels: findings from the A-CHILD longitudinal study.Frontiers in public health · 2026Article
- Parents of Child Psychiatric Patients Report More Adverse Childhood Experiences Compared with Community Samples.Children (Basel, Switzerland) · 2024Article
- Proposed Physiological Mechanisms Underlying the Association between Adverse Childhood Experiences and Mental Health Conditions: A Narrative Review.Children (Basel, Switzerland) · 2024Review
- Eating behaviors as pathways from early childhood adversity to adolescent cardiometabolic risk.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Article
- A role for adverse childhood experiences and depression in preeclampsia.Journal of clinical and translational science · 2024Article
- Article
- Association of early life adversity with cardiovascular disease and its potential mechanisms: a narrative review.Frontiers in public health · 2024Review
- Article
- Association of adverse childhood experiences with lipid profiles and atherogenic risk indices in a middle-to-older aged population.SSM - population health · 2023Article
- Early-life adversity and later-life mental health: a conditional process analysis of sense of coherence and resilience-related resources.Frontiers in child and adolescent psychiatry · 2023Article
- Effect modifications of BMI transition and trajectory in the associations of adverse childhood experiences with new-onset dementia and its subtypes in older US adults.General psychiatry · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies that have examined associations between adverse childhood experiences (ACEs) and cardiometabolic biomarkers in adulthood are limited as they mainly focus on childhood maltreatment. This study aimed to examine the association between a range of prospectively and retrospectively reported ACEs and cardiometabolic biomarkers in mid-adulthood. Multiply-imputed data on 8511 participants from the National Child Development Study (1958 British birth cohort) were used. ACEs were prospectively reported at ages 7, 11 and 16, and retrospectively reported at age 33/44/45. Cardiometabolic outcomes assessed at age 44/45 included glycated haemoglobin (HbA1c), cholesterol (total, low-density lipoprotein (LDL) and high-density lipoprotein (HDL)), triglycerides, blood pressure (systolic and diastolic), body mass index, waist circumference and metabolic syndrome. Parental separation/divorce, physical neglect, emotional neglect and psychological abuse were associated with lower HDL cholesterol. Parental offending and physical neglect were associated with higher triglyceride concentrations. Parental offending was also associated with increased HbA1c. Exposure to 2+ (vs. 0) prospective ACEs was associated with lower HDL cholesterol. All these associations were after adjustment for sex and multiple early life factors. To conclude, several individual ACEs are associated with poorer cardiometabolic risk factor profiles in mid-adulthood. Furthermore, exposure to two or more prospective ACEs is associated with lower HDL cholesterol concentrations in mid-adulthood.
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