Evidence map›Paper›PMID 36238760›Full record

ArticleJournal of inflammation research2022

The Relationship Between Plasma Selenium, Antioxidant Status, Inflammatory Responses and Ischemic Cardiomyopathy: A Case-Control Study Based on Matched Propensity Scores.

Yinhua Luo, Xiaohong He, Linbo Hu, Jinbo Zhao, Ke Su, Yuhua Lei, Yuanhong Li

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of inflammation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07462858 (Development and Efficacy Assessment of Tuna-based), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07462858 nacompletednot on this mapstarted 2025, after this paper: background citation

Development and Efficacy Assessment of Tuna-based (Thunnus Albacares) Nuggets on Cardio-metabolic Risk Factors in Ischemic Cardiomyopathy Patients

TypeinterventionalSponsorUniversity of Lahore Hospital (ULH)Ran2025 to 2026Enrolled120ConditionsIschemic Cardiomyopathy, Obesity, Metabolically BenignArmstuna based nuggets
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yinhua Luo *Cardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Shiyan, People's Republic of China.
Xiaohong He *Centre for Disease Control and Prevention, Enshi Center for Disease Control and Prevention, Enshi Prefecture, People's Republic of China.
Linbo HuHealth Management Centre, Central Hospital of Tujia and Miao Autonomous Prefecture, Enshi Prefecture, People's Republic of China.
Jinbo ZhaoCardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Shiyan, People's Republic of China.
Ke SuCardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Shiyan, People's Republic of China.
Yuhua LeiCardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Shiyan, People's Republic of China.
Yuanhong LiCardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Shiyan, People's Republic of China.
The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture · CNHubei University of Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ischemic cardiomyopathy (ICM) with high morbidity and mortality is closely associated with an abnormal equilibrium of circulation selenium levels. The oxidative stress theory is the most accepted theory of selenium causing ischemic cardiomyopathy. However, the role of inflammatory responses in ICM has received limited attention. Methods: This study included 119 subjects, 43 of whom were patients with ICM, and 76 were healthy controls. Blood specimens were collected from subjects and serum levels of inflammatory and oxidative stress indicators and plasma levels of selenium were measured. Results: When plasma selenium and indicators of inflammation and oxidative stress were compared between groups, plasma selenium levels were significantly lower in the ICM group than in the control group (68.83874 vs 104.39775, Conclusion: Selenium deficiency is strongly associated with the development of ICM, and with levels of inflammation and oxidative stress in patients with ICM. Selenium can prevent the development and delay the progression of ICM by alleviating inflammatory responses.

Indexed as

inflammatory responsesischemic cardiomyopathyoxidative stressselenium

Identifiers

PMID36238760
PMCPMC9553306
OpenAlexW4303936872

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.