Evidence map›Paper›PMID 36238645›Full record

SynthesisOxidative medicine and cellular longevity2022

Efficacy and Safety of Bifidobacterium Quadruple Viable Bacteria Combined with Mesalamine against UC Management: A Systematic Review and Meta-Analysis.

Fei Xie, Shichao Li, Yao Fan, Wusheng Li, Qijun Lv, Xin Sun, Yingshuang Chen, Xiangdong Yang

RetractedOpen access · hybridAbstract readMeta-AnalysisSystematic ReviewRetracted Publication
In one paragraph

Synthesis in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Fei XieThe Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, China.
Shichao LiThe Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, China.
Yao FanThe Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, China.
Wusheng LiThe Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, China.
Qijun LvSouthwest Medical University, China.
Xin SunSouthwest Medical University, China.
Yingshuang ChenSouthwest Medical University, China.
Xiangdong YangThe Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, China.ORCID https://orcid.org/0000-0002-9215-2372
Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To systematically assess effectiveness and safety of Bifidobacterium quadruple viable bacteria combined with mesalamine against ulcerative colitis (UC) in the Asian population. Methods: An electronic search was conducted in PubMed, Embase, Cochrane Library, CNKI, VIP, and Wanfang databases for a random collection of controlled trials of Bifidobacterium quadruple viable bacteria combined with mesalamine against UC. Following data screening and extraction, a Cochrane risk assessment tool was adopted to evaluate the quality of the included studies, and RevMan 5.3 and Stata/SE 15.1 software were used for meta-analysis. Results: Nineteen articles which enrolled 1,707 subjects were included ultimately in this study. The experimental group performed better than the control group in improving the Mayo score (MD = -1.94, 95% CI = (-2.69, -1.19), Conclusion: In conclusion, the current meta-analysis shows that Bifidobacterium quadruple viable bacterium combined with mesalamine has a satisfactory effect in the treatment of UC in China, and its safety is better than that of mesalamine or Bifidobacterium quadruple viable bacteria alone. However, randomized controlled trials with standardized designs and large sample sizes are still needed for further validation.

Indexed as

Colitis, UlcerativeMesalamineBifidobacteriumC-Reactive ProteinHumansInterleukin-4Interleukin-8Superoxide DismutaseTumor Necrosis Factor-alphaC-Reactive ProteinInterleukin-4Interleukin-8MesalamineSuperoxide DismutaseTumor Necrosis Factor-alpha

Identifiers

PMID36238645
PMCPMC9553352
OpenAlexW4301187618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.