Evidence map›Paper›PMID 36238580›Full record

ArticleIJID regions2022

Temporal trend of drug-resistant tuberculosis among Thai children during 2006-2021.

Watsamon Jantarabenjakul, Praon Supradish Na Ayudhya, Piyarat Suntarattiwong, Nattawan Thepnarong, Suwachreepon Rotcheewaphan, Nibondh Udomsantisuk, Juthamanee Moonwong, Papada Kosulvit, Monta Tawan, Tavitiya Sudjaritruk and 1 more

Open access · goldAbstract read
In one paragraph

Article in IJID regions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Watsamon JantarabenjakulDepartment of Pediatrics, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Praon Supradish Na AyudhyaQueen Sirikit Institute of Child Health, Bangkok, Thailand.
Piyarat SuntarattiwongQueen Sirikit Institute of Child Health, Bangkok, Thailand.
Nattawan ThepnarongCenter of Excellence for Pediatric Infectious Diseases and Vaccines, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Suwachreepon RotcheewaphanDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Nibondh UdomsantisukDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Juthamanee MoonwongCenter of Excellence for Pediatric Infectious Diseases and Vaccines, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Papada KosulvitQueen Sirikit Institute of Child Health, Bangkok, Thailand.
Monta TawanCenter of Excellence for Pediatric Infectious Diseases and Vaccines, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Tavitiya SudjaritrukDepartment of Pediatrics, Faculty of Medicine, Chiangmai University, Chiangmai, Thailand.
Thanyawee PuthanakitDepartment of Pediatrics, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Chulalongkorn University · THQueen Sirikit National Institute of Child Health · THChiang Mai University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prevalence of drug-resistant tuberculosis (DR-TB) in adults has stabilized in the past decade. Our study aimed to describe the prevalence of DR-TB in Thai children between 2006 and 2021. Materials and methods: Children younger than 15 years old who had culture-confirmed Results: Among 163 confirmed TB cases (44% as pulmonary TB, 27% as extrapulmonary TB, and 29% with both), the median age (IQR) was 12.2 (7.3-14.2) years. DST was performed in 139 cases (85%), revealing prevalences of all DR-TB, isoniazid-resistant TB (Hr-TB), and rifampicin monoresistant/multidrug-resistant TB (Rr/MDR-TB) of 21.6% (95% CI 14.7-28.4), 10.8% (95% CI 5.6-16.0%), and 2.9% (95% CI 0.1-5.7%), respectively. The DR-TB rates did not differ significantly between 2006-2013, 2014-2018, and 2019-2021 ( Conclusion: The prevalence of DR-TB in Thai children was stable. However, one-tenth of DR-TB cases confirmed with DST were Hr-TB, which required adjustment of the treatment regimen. The pre-XDR cases should be closely monitored.

Indexed as

childrenDR-TB, Drug resistant tuberculosisdrug-resistant tuberculosisfluoroquinoloneHr-TB, Isoniazid-monoresistant tuberculosisisoniazid-monoresistant tuberculosis (Hr-TB)MDR-TB, Multidrug-resistant tuberculosismultidrug-resistant tuberculosis (MDR-TB)pre-extensively drug-resistant tuberculosis (pre-XDR-TB)Pre-XDR-TB, Pre-extensively drug-resistant tuberculosisrifampicin-monoresistant tuberculosis (Rr-TB)Rr-TB, Rifampicin-monoresistant tuberculosis

Identifiers

PMID36238580
PMCPMC9550601
OpenAlexW4296242501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.