Evidence map›Paper›PMID 36238565›Full record

ArticleFrontiers in pharmacology2022

Effect of long-term cannabidiol on learning and anxiety in a female Alzheimer's disease mouse model.

Rose Chesworth, David Cheng, Chloe Staub, Tim Karl

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Cannabidiol prevents cognitive and social deficits in a male rat model of Alzheimer's disease through CB1 activation and inflammation modulation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  7. Review
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  16. Synergetic effect of β-asarone and cannabidiol against Aβ aggregationComputational and structural biotechnology journal · 2023
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Rose ChesworthSchool of Medicine, Western Sydney University, Campbelltown, NSW, Australia.
David ChengNeuroscience Research Australia, Randwick, NSW, Australia.
Chloe StaubSchool of Medicine, Western Sydney University, Campbelltown, NSW, Australia.
Tim KarlSchool of Medicine, Western Sydney University, Campbelltown, NSW, Australia.
Camden and Campbelltown Hospitals · AUNeuroscience Research Australia · AUWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabidiol is a promising potential therapeutic for neurodegenerative diseases, including Alzheimer's disease (AD). Our laboratory has shown that oral CBD treatment prevents cognitive impairment in a male genetic mouse model of AD, the

Indexed as

Alzheimer’s diseaseamyloid precursor proteinbehaviourcannabidiol (CBD)femalepresenilin 1spatial memory

Identifiers

PMID36238565
PMCPMC9551202
OpenAlexW4297425215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.