ArticleFrontiers in nutrition2022
Uncovering the biogeography of the microbial commmunity and its association with nutrient metabolism in the intestinal tract using a pig model.
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 17 citations in OpenAlex.
- B-MASTER: scalable Bayesian multivariate regression for master predictor discovery in colorectal cancer microbiome-metabolite profiles.Bioinformatics (Oxford, England) · 2026Article
- pH-responsive microgels containing multifunctional ginsenoside Rh2-based liposomes remodel intestinal environment to enhance celastrol therapy for ulcerative colitis.Materials today. Bio · 2026Article
- A manually curated pig gut microbiome dataset for precision feeding.Scientific data · 2026Article
- Integrative clustering by colonic volatile fatty acids reveals microbiota and host physiological variation in weaned piglets.Journal of animal science and biotechnology · 2026Article
- Gut microbiota and uveitis: exploring novel mechanisms of inflammatory ocular diseases via the gut-eye axis.Frontiers in microbiology · 2026Review
- Polyphenols ameliorate metabolic disorders by remodeling gut microbiota and regulating Nrf2/NF-κB signaling pathways.Frontiers in microbiology · 2026Review
- Leptin receptor gene influences pig gut microbiota both through feed intake and independently.Animal microbiome · 2025Article
- Effect of Dietary Neutral Detergent Fiber Intake on Improving Fecal Consistency in Gestating Gilts.Animals : an open access journal from MDPI · 2025Article
- Identification of Fecal Microbiota and Related Metabolites Associated with Feed Efficiency in DLY Pigs.Animals : an open access journal from MDPI · 2025Article
- Exploring the cecal microbial community associated with fat deposition in sheep and its possible pathways of action.Microbiology spectrum · 2025Article
- Intestinal fungi biogeography, succession and its association with diarrhea in pigs.Journal of animal science and biotechnology · 2025Article
- Variation of Meat Quality and Relationship to Gut Microbiota Among Different Pig Breeds.Microbial biotechnology · 2025Article
- Article
- Topological and spatial heterogeneity of gut microbiota co-abundance networks in pigs revealed by using large-scale samples.Frontiers in microbiology · 2025Review
- Survey of gut microbial biogeography and their functional niche in the grow-finishing swine of ordinary feeding.Frontiers in microbiology · 2025Article
- Aberrant bowel movement frequencies coincide with increased microbe-derived blood metabolites associated with reduced organ function.Cell reports. Medicine · 2024Article
- Generally-healthy individuals with aberrant bowel movement frequencies show enrichment for microbially-derived blood metabolites associated with reduced kidney function.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gut microbiota is a complex ecosystem that is essential for the metabolism, immunity and health of the host. The gut microbiota also plays a critical role in nutrient absorption and metabolism, and nutrients can influence the growth and composition of the gut microbiota. To gain a better understanding of the relationship between the gut microbial composition and nutrient metabolism, we used a pig model by collecting the contents of the different intestinal locations from six pigs to investigate microbial composition in different intestinal locations based on 16S rRNA gene sequencing and the concentrations of short-chain fatty acids (SCFAs), amino acids, fat, and crude ash in different intestinal locations using gas chromatography and chemical analysis. The results showed that the richness and diversity of intestinal microbial communities gradually increased from the small intestine to the large intestine. The relative abundance of Proteobacteria was higher in the jejunum and ileum, whereas the proportion of Firmicutes was higher in the cecum and colon. The concentrations of SCFAs were higher in the cecum and colon (
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