Evidence map›Paper›PMID 36238426›Full record

ReviewHealth psychology and behavioral medicine2022

Impact of prenatal alcohol exposure on neurodevelopmental outcomes: a systematic review.

Joanna Ting Wai Chu, Jessica McCormack, Samantha Marsh, Alesha Wells, Holly Wilson, Chris Bullen

Abstract readReview
In one paragraph

Review in Health psychology and behavioral medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  6. Evaluating the role of strengths and protective factors for youth with FASD and criminal legal system involvement: a scoping review.Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2026
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  7. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joanna Ting Wai ChuNational Institute for Health Innovation, School of Population Health, University of Auckland, Auckland, New Zealand.
Jessica McCormackNational Institute for Health Innovation, School of Population Health, University of Auckland, Auckland, New Zealand.
Samantha MarshSocial and Community Health, School of Population Health, University of Auckland, Auckland, New Zealand.
Alesha WellsDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.
Holly WilsonNational Institute for Health Innovation, School of Population Health, University of Auckland, Auckland, New Zealand.
Chris BullenNational Institute for Health Innovation, School of Population Health, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0001-6807-2930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prenatal exposure to alcohol (PAE) represents a significant public health concern. Previous research linking PAE to neurodevelopmental outcomes has been mixed and often has limited focus on residual confounding or moderating factors. Methods: A systematic review of prospective cohort studies ( Results: Thirty longitudinal cohort studies met the inclusion criteria. Evidence of the impact of PAE was mixed across domains. We found no evidence that PAE affects executive function, but there were impacts on motor skills, cognition, language, academic achievement, attention, affect regulation, and adaptive behaviour. The most consistent adverse effect was on affect regulation (nine out of thirteen studies, six of which found an association between heavy alcohol consumption or binge drinking during pregnancy). We found no protective factors. Few studies controlled for variables in the postnatal environment. Discussion: This review was unable to conclude a safe level of alcohol consumption during pregnancy. Methodological improvements are needed to improve the quality and consistency in which PAE is studied. Further research into residual confounding variables is vital, including a greater focus on the postpartum environment.

Indexed as

alcoholneurodevelopmental outcomespregnancyPrenatal alcohol exposuresystematic review

Identifiers

PMID36238426
PMCPMC9553152

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.